| Entry |
|
|---|
| Name |
Magnesium clofibrate (INN);
Clofibric acid magnesium salt;
Clofibrate Magnesico Chobet (TN) |
|---|
| Formula |
C20H20Cl2MgO6
|
|---|
| Exact mass |
450.0487
|
|---|
| Mol weight |
451.58
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00358): | D00279<JP> |
|
|---|
| Efficacy |
Antihyperlipidemic, Triglyceride synthesis inhibitor, Peroxisome proliferator-activated receptor (PPAR) alpha agonist |
|---|
| Comment |
Clofibrate derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04920 | Adipocytokine signaling pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07222 | Peroxisome proliferator-activated receptor (PPAR) agonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C10 LIPID MODIFYING AGENTS
C10A LIPID MODIFYING AGENTS, PLAIN
C10AB Fibrates
C10AB01 Clofibrate
D07724 Magnesium clofibrate (INN)
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
DG00358 Clofibrate
D07724 Magnesium clofibrate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C1 (PPARA)
D07724 Magnesium clofibrate (INN)
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
DG00358 Clofibrate
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 C8y C 20.1600 -18.3400
2 O2a O 21.3500 -17.6400
3 C1d C 22.5400 -18.3400
4 C7a C 23.8000 -17.6400
5 O7a O 24.9900 -18.3400
6 Z Mg 26.3200 -17.6400
7 O7a O 28.0000 -18.3400
8 C7a C 29.1900 -17.6400
9 C1d C 30.3800 -18.2700
10 O2a O 31.6400 -17.5700
11 C8y C 32.8300 -18.2700
12 C1a C 21.5600 -19.3200
13 C1a C 23.5900 -19.3200
14 O6a O 23.8000 -16.2400
15 O6a O 29.1900 -16.2400
16 C1a C 29.4000 -19.3200
17 C1a C 31.3600 -19.3200
18 C8x C 32.8300 -19.6700
19 C8x C 34.0200 -20.3700
20 C8y C 35.2100 -19.6700
21 C8x C 35.2100 -18.2700
22 C8x C 34.0200 -17.5700
23 C8x C 18.9000 -17.6400
24 C8x C 17.7100 -18.3400
25 C8y C 17.7100 -19.7400
26 C8x C 18.9000 -20.4400
27 C8x C 20.1600 -19.7400
28 X Cl 16.5200 -20.4400
29 X Cl 36.4700 -20.3700
BOND 30
1 7 8 1
2 8 15 2
3 9 16 1
4 8 9 1
5 9 17 1
6 4 5 1
7 9 10 1
8 2 3 1
9 10 11 1
10 5 6 1
11 11 18 2
12 18 19 1
13 19 20 2
14 20 21 1
15 21 22 2
16 22 11 1
17 3 12 1
18 1 2 1
19 3 13 1
20 6 7 1
21 4 14 2
22 1 23 2
23 23 24 1
24 24 25 2
25 25 26 1
26 26 27 2
27 27 1 1
28 3 4 1
29 25 28 1
30 20 29 1
|
|---|
