KEGG   DRUG: Cloxacillin
Entry
D07733                      Drug                                   
Name
Cloxacillin (INN);
Orbenin (TN)
Formula
C19H18ClN3O5S
Exact mass
435.0656
Mol weight
435.8813
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penicillin
 DG01779  beta-Lactamase resistant penicillin
Remark
Same as: C06923
ATC code: J01CF02
Chemical structure group: DG00541
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CF Beta-lactamase resistant penicillins
     J01CF02 Cloxacillin
      D07733  Cloxacillin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01713  Penicillin skeleton group
    DG01480  Penicillin
     DG00541  Cloxacillin
      D07733  Cloxacillin
  DG01779  beta-Lactamase resistant penicillin
   DG00541  Cloxacillin
    D07733  Cloxacillin
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   beta-Lactamase resistant penicillin
    D07733  Cloxacillin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01713  Penicillin skeleton group
    DG01480  Penicillin
     DG00541  Cloxacillin
  DG01779  beta-Lactamase resistant penicillin
   DG00541  Cloxacillin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   beta-Lactamase resistant penicillin
    DG00541  Cloxacillin
Other DBs
CAS: 61-72-3
PubChem: 51092029
ChEBI: 49566
PDB-CCD: CXN[PDBj]
LigandBox: D07733
NIKKAJI: J4.818F
LinkDB
KCF data

ATOM        29
            1   C1y C    25.6200  -17.2900
            2   C5x C    25.6200  -18.6900
            3   N1y N    27.0200  -18.6900
            4   C1y C    27.0200  -17.2900
            5   C1y C    28.3500  -19.1100
            6   C1z C    29.1200  -17.9900
            7   S2x S    28.3500  -16.8700
            8   C1a C    30.1000  -18.9700
            9   C1a C    30.1000  -17.0100
            10  C6a C    28.7700  -20.4400
            11  O6a O    30.1700  -20.4400
            12  O6a O    28.0000  -21.5600
            13  N1b N    24.4300  -16.5900
            14  C5a C    23.2400  -17.2900
            15  O5x O    24.4300  -19.3200
            16  O5a O    23.2400  -18.6900
            17  C8y C    21.9800  -16.5900
            18  C8y C    21.9800  -15.1900
            19  O2x O    20.6500  -14.7700
            20  N5x N    19.8800  -15.8900
            21  C8y C    20.6500  -17.0100
            22  C1a C    23.1000  -14.3500
            23  C8y C    20.6500  -18.4100
            24  C8y C    19.3900  -19.1800
            25  C8x C    19.3900  -20.5800
            26  C8x C    20.6500  -21.2800
            27  C8x C    21.9100  -20.5800
            28  C8x C    21.9100  -19.1100
            29  X   Cl   18.2000  -18.4100
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 1
            22   20  21 2
            23   17  21 1
            24   18  22 1
            25   21  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   23  28 1
            32   24  29 1

» Japanese version   » Back

KEGG   DRUG: Cloxacillin sodium
Entry
D02231                      Drug                                   
Name
Cloxacillin sodium (USP);
Cloxacillin sodium hydrate (JP18);
Cloxapen (TN);
Tegopen (TN)
Formula
C19H17ClN3O5S. Na. H2O
Exact mass
475.0581
Mol weight
475.8784
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penicillin
 DG01779  beta-Lactamase resistant penicillin
Remark
Same as: C14010
ATC code: J01CF02
Chemical structure group: DG00541
Product (mixture): D02502<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CF Beta-lactamase resistant penicillins
     J01CF02 Cloxacillin
      D02231  Cloxacillin sodium (USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01713  Penicillin skeleton group
    DG01480  Penicillin
     DG00541  Cloxacillin
      D02231  Cloxacillin sodium
  DG01779  beta-Lactamase resistant penicillin
   DG00541  Cloxacillin
    D02231  Cloxacillin sodium
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   beta-Lactamase resistant penicillin
    D02231  Cloxacillin sodium (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02231  Cloxacillin sodium hydrate
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01713  Penicillin skeleton group
    DG01480  Penicillin
     DG00541  Cloxacillin
  DG01779  beta-Lactamase resistant penicillin
   DG00541  Cloxacillin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   beta-Lactamase resistant penicillin
    DG00541  Cloxacillin
Other DBs
CAS: 7081-44-9
PubChem: 7849290
ChEBI: 34978
LigandBox: D02231
NIKKAJI: J1.591.904C
LinkDB
KCF data

ATOM        31
            1   C1y C    27.5483  -14.8950
            2   C5x C    27.5483  -16.2592
            3   N1y N    28.9125  -16.2592
            4   C1y C    28.9125  -14.8950
            5   C1y C    30.2085  -16.6684
            6   C1z C    31.0270  -15.5771
            7   S2x S    30.2085  -14.4858
            8   C1a C    31.9819  -16.5320
            9   C1a C    31.9819  -14.6222
            10  C6a C    30.6859  -18.0326
            11  O6a O    32.0501  -18.0326 #-
            12  O6a O    29.8674  -19.1240
            13  N1b N    26.3888  -14.2129
            14  C5a C    25.2292  -14.8950
            15  O5x O    26.3888  -16.9413
            16  O5a O    25.2292  -16.2592
            17  C8y C    24.0015  -14.2129
            18  C8y C    24.0015  -12.8488
            19  O2x O    22.7040  -12.4272
            20  N5x N    21.9022  -13.5308
            21  C8y C    22.7040  -14.6345
            22  C1a C    25.1051  -12.0469
            23  C8y C    22.7040  -16.0345
            24  C8y C    21.4757  -16.7439
            25  C8x C    21.4759  -18.1439
            26  C8x C    22.6884  -18.8437
            27  C8x C    23.9167  -18.1343
            28  C8x C    23.9165  -16.7343
            29  X   Cl   20.2680  -16.0468
            30  Z   Na   33.6189  -18.1008 #+
            31  O0  O    33.8917  -19.8743
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 1
            22   20  21 2
            23   17  21 1
            24   18  22 1
            25   21  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   23  28 1
            32   24  29 1

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