KEGG   DRUG: FluindioneHelp
Entry
D07969                      Drug                                   

Name
Fluindione (INN);
Previsccan (TN)
Formula
C15H9FO2
Exact mass
240.0587
Mol weight
240.2292
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01708  Coumarin anticoagulant
  DG01761  Phenindion type coumarin derivative
 DG01950  Antithrombotic agent
  DG01708  Coumarin anticoagulant
   DG01761  Phenindion type coumarin derivative
Remark
ATC code: B01AA12
Efficacy
Anticoagulant, Vitamin K antagonist
Comment
Phenindione (indandione) derivative
Target
VKORC1 [HSA:79001] [KO:K05357]
  Pathway
hsa00130  Ubiquinone and other terpenoid-quinone biosynthesis
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AA Vitamin K antagonists
     B01AA12 Fluindione
      D07969  Fluindione (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Vitamin-K-epoxide reductase
    VKORC1
     D07969  Fluindione (INN)
BRITE hierarchy
Other DBs
CAS: 957-56-2
PubChem: 96024664
ChEMBL: CHEMBL24924
LigandBox: D07969
NIKKAJI: J7.190K
LinkDB All DBs
KCF data Show

ATOM        18
            1   C8x C    12.9500  -19.5300
            2   C8x C    12.9500  -20.9300
            3   C8x C    14.1624  -21.6300
            4   C8y C    15.3749  -20.9300
            5   C8y C    15.3749  -19.5300
            6   C8x C    14.1624  -18.8300
            7   C5x C    16.7064  -21.3626
            8   C1y C    17.5293  -20.2300
            9   C5x C    16.7064  -19.0974
            10  C8y C    18.9000  -20.2300
            11  C8x C    19.6000  -21.4424
            12  C8x C    21.0000  -21.4424
            13  C8y C    21.7000  -20.2300
            14  C8x C    21.0000  -19.0176
            15  C8x C    19.6000  -19.0176
            16  O5x O    17.1375  -22.6894
            17  O5x O    17.1375  -17.7706
            18  X   F    23.1000  -20.2300
BOND        20
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    5   9 1
            11    8  10 1
            12   10  11 2
            13   11  12 1
            14   12  13 2
            15   13  14 1
            16   14  15 2
            17   10  15 1
            18    7  16 2
            19    9  17 2
            20   13  18 1

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