KEGG   DRUG: FluocortinHelp
Entry
D07972                      Drug                                   

Name
Fluocortin (INN)
Formula
C22H27FO5
Exact mass
390.1843
Mol weight
390.4452
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
Same as: C21553
ATC code: D07AB04
Chemical structure group: DG00413
Efficacy
Anti-inflammatory, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AB Corticosteroids, moderately potent (group II)
     D07AB04 Fluocortin
      D07972  Fluocortin (INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D07972  Fluocortin (INN)
BRITE hierarchy
Other DBs
CAS: 33124-50-4
PubChem: 96024667
LigandBox: D07972
NIKKAJI: J17.579J
LinkDB All DBs
KCF data Show

ATOM        28
            1   C2x C    18.9000  -24.6400
            2   C5x C    18.9000  -25.9700
            3   C2x C    20.0900  -26.6700
            4   C2y C    21.2800  -25.9700
            5   C1z C    21.2800  -24.6400
            6   C2x C    20.0900  -23.9400
            7   C1y C    22.5400  -26.6700
            8   C1x C    23.7300  -25.9700
            9   C1y C    23.7300  -24.6400
            10  C1y C    22.5400  -23.9400
            11  C1y C    24.9200  -23.9400
            12  C1z C    24.9200  -22.5400
            13  C1x C    23.7300  -21.8400
            14  C1y C    22.5400  -22.5400
            15  O5x O    17.7100  -26.6700
            16  C1a C    21.2800  -23.2400
            17  O1a O    21.2800  -21.8400
            18  C1a C    24.9200  -21.1400
            19  X   F    22.5400  -28.0700
            20  C1x C    27.3449  -23.9400
            21  C1y C    27.3449  -22.5400
            22  C1y C    26.1324  -21.8400
            23  C1a C    28.5760  -21.8290
            24  C5a C    26.1324  -20.3002
            25  C6a C    24.9032  -19.5904
            26  O5a O    27.3280  -19.6098
            27  O6a O    23.6993  -20.2854
            28  O6a O    24.9034  -18.2001
BOND        31
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17    2  15 2
            18    5  16 1 #Up
            19   14  17 1 #Up
            20   12  18 1 #Up
            21    7  19 1 #Down
            22   11  20 1
            23   20  21 1
            24   21  22 1
            25   12  22 1
            26   21  23 1 #Down
            27   22  24 1 #Up
            28   24  25 1
            29   24  26 2
            30   25  27 1
            31   25  28 2

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