| Entry |
|
|---|
| Name |
Fluprednidene acetate;
Fluprednidene 21-acetate;
Decoderm (TN) |
|---|
| Formula |
C24H29FO6
|
|---|
| Exact mass |
432.1948
|
|---|
| Mol weight |
432.48
|
|---|
| Structure |
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| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AB Corticosteroids, moderately potent (group II)
D07AB07 Fluprednidene
D07980 Fluprednidene acetate
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XB Corticosteroids, moderately potent, other combinations
D07XB03 Fluprednidene
D07980 Fluprednidene acetate
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00414 Fluprednidene
D07980 Fluprednidene acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D07980 Fluprednidene acetate
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00414 Fluprednidene
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 31
1 C1z C 25.9000 -17.3600
2 C1y C 25.9000 -18.7600
3 C1x C 28.2800 -18.7600
4 C2y C 28.2800 -17.3600
5 C1z C 27.0900 -16.6600
6 C1x C 24.7100 -16.6600
7 C1y C 23.5200 -17.3600
8 C1z C 23.5200 -18.7600
9 C1y C 24.7100 -19.4600
10 C1z C 22.3300 -19.4600
11 C2y C 22.3300 -20.7900
12 C1x C 23.5200 -21.4900
13 C1x C 24.7100 -20.7900
14 C2x C 21.1400 -18.7600
15 C2x C 19.9500 -19.4600
16 C5x C 19.9500 -20.7900
17 C2x C 21.1400 -21.4900
18 C2a C 29.6100 -17.0100
19 C5a C 27.0900 -15.3300
20 C1b C 28.0000 -14.3500
21 O7a O 29.3300 -14.7000
22 O1a O 28.2800 -16.0300
23 C1a C 25.9000 -16.0300
24 O1a O 22.3300 -16.6600
25 C1a C 22.3300 -18.0600
26 X F 23.5200 -20.0900
27 O5x O 18.7600 -21.4900
28 O5a O 25.7600 -14.7700
29 C7a C 30.3155 -13.7056
30 C1a C 31.6677 -14.0615
31 O6a O 29.9503 -12.3670
BOND 34
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 1 6 1
7 6 7 1
8 7 8 1
9 8 9 1
10 9 2 1
11 8 10 1
12 10 11 1
13 11 12 1
14 12 13 1
15 13 9 1
16 10 14 1
17 14 15 2
18 15 16 1
19 16 17 1
20 17 11 2
21 4 18 2
22 5 19 1 #Up
23 19 20 1
24 20 21 1
25 5 22 1 #Down
26 1 23 1 #Up
27 7 24 1 #Up
28 10 25 1 #Up
29 8 26 1 #Down
30 16 27 2
31 19 28 2
32 21 29 1
33 29 30 1
34 29 31 2
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