| Entry |
|
|---|
| Name |
Vosaroxin (USAN);
Voreloxin |
|---|
| Formula |
C18H19N5O4S
|
|---|
| Exact mass |
401.1158
|
|---|
| Mol weight |
401.44
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01529 Topoisomerase inhibitor
DG01527 Topoisomerase II inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Topoisomerase II inhibitor |
|---|
| Comment |
Name previously used: Voreloxin
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XX Other antineoplastic agents
L01XX53 Vosaroxin
D08024 Vosaroxin (USAN)
Drug groups [BR:br08330]
Antineoplastic
DG01529 Topoisomerase inhibitor
DG01527 Topoisomerase II inhibitor
D08024 Vosaroxin
Target-based classification of drugs [BR:br08310]
Enzymes
Isomerases (EC5)
DNA topoisomerase
TOP2
D08024 Vosaroxin (USAN)
|
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| Other DBs |
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|---|
| LinkDB |
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| KCF data |
ATOM 28
1 C8y C 25.3400 -21.0700
2 C8y C 25.3400 -22.4700
3 N4y N 26.5300 -23.1700
4 C8x C 27.7900 -22.4700
5 C8y C 27.7900 -21.0700
6 C8y C 26.5300 -20.3700
7 C8x C 24.1500 -20.3700
8 C8x C 22.8900 -21.0700
9 C8y C 22.8900 -22.4700
10 N5x N 24.1500 -23.1700
11 O5x O 26.5300 -18.9700
12 C6a C 28.9800 -20.3700
13 O6a O 30.1700 -21.0700
14 O6a O 28.9800 -18.9700
15 C8y C 26.5300 -24.5700
16 N1y N 21.7000 -23.1700
17 N5x N 25.4100 -25.4100
18 C8x C 25.8300 -26.7400
19 C8x C 27.2300 -26.7400
20 S2x S 27.7200 -25.4100
21 C1x C 20.5800 -22.4000
22 C1y C 19.4600 -23.1700
23 C1y C 19.8800 -24.5000
24 C1x C 21.2800 -24.5000
25 N1b N 18.1300 -22.7500
26 C1a C 17.0800 -23.7300
27 O2a O 19.0400 -25.6200
28 C1a C 17.6400 -25.4800
BOND 31
1 1 2 2
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 2 10 1
12 6 11 2
13 5 12 1
14 12 13 1
15 12 14 2
16 3 15 1
17 9 16 1
18 15 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 15 20 1
23 16 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 16 24 1
28 22 25 1 #Up
29 25 26 1
30 23 27 1 #Down
31 27 28 1
|
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