| Entry |
|
|---|
| Name |
Homochlorcyclizine (INN) |
|---|
| Formula |
C19H23ClN2
|
|---|
| Exact mass |
314.1550
|
|---|
| Mol weight |
314.85
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01328 Homochlorcyclizine
D08041 Homochlorcyclizine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D08041 Homochlorcyclizine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01328 Homochlorcyclizine
|
|---|
| Other DBs |
|
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| LinkDB |
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| KCF data |
ATOM 22
1 C1x C 22.7616 -13.8610
2 C1x C 22.6076 -12.4741
3 C1x C 23.5569 -11.4140
4 N1y N 24.9822 -11.6067
5 N1y N 23.9635 -14.5699
6 C1x C 25.6848 -12.7501
7 C1x C 25.2764 -14.1292
8 C1a C 25.6911 -10.4048
9 C8y C 22.6628 -16.6378
10 C1c C 23.9264 -16.0060
11 C8y C 25.1283 -16.7150
12 C8x C 25.1613 -18.1511
13 C8x C 26.2932 -18.8600
14 C8y C 27.4967 -18.1929
15 C8x C 27.5337 -16.7567
16 C8x C 26.3318 -16.0478
17 C8x C 21.4609 -15.9289
18 C8x C 20.2574 -16.5960
19 C8x C 20.1957 -17.9367
20 C8x C 21.4577 -18.6810
21 C8x C 22.6612 -18.0138
22 X Cl 28.6986 -18.9018
BOND 24
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 4 8 1
9 9 10 1
10 5 10 1
11 10 11 1
12 11 12 2
13 12 13 1
14 13 14 2
15 14 15 1
16 15 16 2
17 11 16 1
18 9 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 9 21 1
24 14 22 1
|
|---|
