KEGG   DRUG: Incadronic acid
Entry
D08073                      Drug                                   
Name
Incadronic acid (INN)
Formula
C8H19NO6P2
Exact mass
287.0688
Mol weight
287.1871
Structure
Simcomp
Class
Musculo-skeletal system agent
 DG03232  Osteoporosis agent
  DG01600  Bisphosphonate
Remark
Chemical structure group: DG01266
Efficacy
Antiresorptive, Farnesylpyrophosphate synthetase inhibitor
Comment
Bisphosphonate
Target
FDPS [HSA:2224] [KO:K00787]
  Pathway
hsa00900  Terpenoid backbone biosynthesis
Interaction
Brite
Drug groups [BR:br08330]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   DG01600  Bisphosphonate
    DG01266  Incadronic acid
     D08073  Incadronic acid
Target-based classification of drugs [BR:br08310]
 Enzymes
  Transferases (EC2)
   Alkyl/Aryl transferases
    FDPS
     D08073  Incadronic acid (INN)
Drug groups [BR:br08330]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   DG01600  Bisphosphonate
    DG01266  Incadronic acid
Other DBs
CAS: 124351-85-5
PubChem: 51092065
LigandBox: D08073
LinkDB
KCF data

ATOM        17
            1   C1x C    21.9883   -8.5934
            2   C1x C    23.0850   -7.7298
            3   C1x C    24.4503   -8.0412
            4   C1y C    25.0521   -9.2943
            5   C1x C    21.9883  -10.0023
            6   C1x C    24.4512  -10.5615
            7   C1x C    23.0850  -10.8731
            8   N1b N    26.4579   -9.2908
            9   C1c C    27.1688  -10.5147
            10  P1b P    28.5578  -10.5111
            11  P1b P    26.4762  -11.7213
            12  O1c O    25.7763  -12.9336
            13  O1c O    25.2639  -11.0214
            14  O1c O    27.6885  -12.4213
            15  O1c O    29.9577  -10.5111
            16  O1c O    28.5578   -9.1112
            17  O1c O    28.5578  -11.9110
BOND        17
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     4   8 1
            9     8   9 1
            10    9  10 1
            11    9  11 1
            12   11  12 1
            13   11  13 1
            14   11  14 2
            15   10  15 1
            16   10  16 1
            17   10  17 2

» Japanese version   » Back

DBGET integrated database retrieval system