| Entry |
|
|---|
| Name |
Ketorolac (INN);
Toradol (TN) |
|---|
| Formula |
C15H13NO3
|
|---|
| Exact mass |
255.0895
|
|---|
| Mol weight |
255.2686
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
|
|---|
| Remark |
| Product (DG00751): | D00813<US> |
| Product (mixture): | D10837<US> |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, COX inhibitor |
|---|
| Comment |
Nonsteroidal anti-inflammatory drug (NSAID)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AB Acetic acid derivatives and related substances
M01AB15 Ketorolac
D08104 Ketorolac (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BC Antiinflammatory agents, non-steroids
S01BC05 Ketorolac
D08104 Ketorolac (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG00751 Ketorolac
D08104 Ketorolac
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D08104 Ketorolac (INN)
PTGS2 (COX2)
D08104 Ketorolac (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG00751 Ketorolac
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 19
1 N4y N 24.8500 -17.0800
2 C8y C 25.9700 -17.9200
3 C8y C 23.7300 -17.9900
4 C1x C 25.2700 -15.7500
5 C1y C 27.0900 -17.0800
6 C8x C 25.5500 -19.2500
7 C5a C 22.4700 -17.2200
8 C8x C 24.1500 -19.2500
9 C1x C 26.6000 -15.7500
10 C6a C 28.2800 -17.7800
11 C8y C 21.2800 -17.9900
12 O5a O 22.4700 -15.8200
13 O6a O 29.5400 -17.0800
14 O6a O 28.2800 -19.1800
15 C8x C 21.2800 -19.3900
16 C8x C 20.0200 -17.2900
17 C8x C 20.0200 -20.0900
18 C8x C 18.8300 -17.9900
19 C8x C 18.8300 -19.3900
BOND 21
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 2
6 3 7 1
7 3 8 2
8 4 9 1
9 5 10 1
10 7 11 1
11 7 12 2
12 10 13 1
13 10 14 2
14 11 15 2
15 11 16 1
16 15 17 1
17 16 18 2
18 17 19 2
19 5 9 1
20 6 8 1
21 18 19 1
|
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