KEGG   DRUG: Liothyronine hydrochloride
Entry
D08129                      Drug                                   
Name
Liothyronine hydrochloride;
Thyrotradin (TN)
Formula
C15H12I3NO4. HCl
Exact mass
686.7667
Mol weight
687.4344
Structure
Simcomp
Class
Hormonal agent
 DG01953  Thyroid preparation
  DG01608  Thyroid hormone replenisher
Remark
Chemical structure group: DG01372
Product (DG01372): D01011<JP/US>
Efficacy
Replenisher (thyroid hormone)
Target
NR1A (THR) [HSA:7067 7068] [KO:K05547 K08362]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07043  Antineoplastics - hormones
Brite
Drug groups [BR:br08330]
 Hormonal agent
  DG01953  Thyroid preparation
   DG01608  Thyroid hormone replenisher
    DG01372  Liothyronine
     D08129  Liothyronine hydrochloride
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Thyroid hormone receptor (THR)
    NR1A (THR)
     D08129  Liothyronine hydrochloride
Drug groups [BR:br08330]
 Hormonal agent
  DG01953  Thyroid preparation
   DG01608  Thyroid hormone replenisher
    DG01372  Liothyronine
Other DBs
CAS: 6138-47-2
PubChem: 96024819
LigandBox: D08129
NIKKAJI: J231.516E
LinkDB
KCF data

ATOM        24
            1   C8y C    24.7800  -17.9200
            2   O2a O    25.9700  -18.6200
            3   C8y C    23.5900  -18.6200
            4   C8y C    24.7800  -16.5200
            5   C8y C    27.2300  -19.3200
            6   C8x C    22.3300  -17.9200
            7   X   I    23.5900  -20.0200
            8   C8x C    23.5900  -15.8200
            9   X   I    25.9700  -15.8200
            10  C8x C    28.4200  -18.6200
            11  C8x C    27.2300  -20.7200
            12  C8y C    22.3300  -16.5200
            13  C8y C    29.6100  -19.3200
            14  C8x C    28.4200  -21.4200
            15  C1b C    21.1400  -15.8200
            16  C8y C    29.6100  -20.7200
            17  X   I    30.8700  -18.6200
            18  C1c C    19.9500  -16.5200
            19  O1a O    30.8700  -21.4200
            20  C6a C    18.6900  -15.8200
            21  N1a N    19.9500  -17.9200
            22  O6a O    17.5000  -16.5200
            23  O6a O    18.6900  -14.4200
            24  X   Cl   34.2300  -19.3200
BOND        24
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     4   8 2
            8     4   9 1
            9     5  10 1
            10    5  11 2
            11    6  12 2
            12   10  13 2
            13   11  14 1
            14   12  15 1
            15   13  16 1
            16   13  17 1
            17   15  18 1
            18   16  19 1
            19   18  20 1
            20   18  21 1 #Down
            21   20  22 1
            22   20  23 2
            23    8  12 1
            24   14  16 2

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