| Entry |
|
|---|
| Name |
Molindone (INN) |
|---|
| Formula |
C16H24N2O2
|
|---|
| Exact mass |
276.1838
|
|---|
| Mol weight |
276.37
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
|
|---|
| Remark |
| Product (DG00891): | D00796<US> |
|
|---|
| Efficacy |
Antipsychotic, Dopamine D2 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AE Indole derivatives
N05AE02 Molindone
D08226 Molindone (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00891 Molindone
D08226 Molindone
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D08226 Molindone (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00891 Molindone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 20
1 C8y C 22.3300 -17.9200
2 C8y C 22.3300 -16.5200
3 C8y C 21.0000 -18.3400
4 C5x C 23.5200 -18.6200
5 N4x N 21.0000 -16.1000
6 C1x C 23.5200 -15.8200
7 C8y C 20.1600 -17.2200
8 C1b C 20.5800 -19.6700
9 C1y C 24.7100 -17.9200
10 O5x O 23.5200 -20.0200
11 C1x C 24.7100 -16.5200
12 C1a C 18.7600 -17.2200
13 C1a C 19.1800 -20.0200
14 C1b C 25.9700 -18.6200
15 N1y N 27.1600 -17.9200
16 C1x C 28.3500 -18.6200
17 C1x C 27.1600 -16.5200
18 C1x C 29.6100 -17.9200
19 C1x C 28.3500 -15.8200
20 O2x O 29.6100 -16.5200
BOND 22
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 1
9 4 10 2
10 6 11 1
11 7 12 1
12 8 13 1
13 9 14 1
14 14 15 1
15 15 16 1
16 15 17 1
17 16 18 1
18 17 19 1
19 18 20 1
20 5 7 1
21 9 11 1
22 19 20 1
|
|---|
