KEGG   DRUG: NaftifineHelp
Entry
D08245                      Drug                                   

Name
Naftifine (INN)
Formula
C21H21N
Exact mass
287.1674
Mol weight
287.3981
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
Same as: C08071
ATC code: D01AE22
Chemical structure group: DG00377
Product (DG00377): D00883<US>
Efficacy
Antifungal, Ergosterol biosynthesis inhibitor
Comment
Allylamine derivative
Target
squalene epoxidase [KO:K00511]
  Pathway
ko00100  Steroid biosynthesis
Structure map
map07026  Antifungal agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AE Other antifungals for topical use
     D01AE22 Naftifine
      D08245  Naftifine (INN)
USP drug classification [BR:br08302]
 Antifungals
  Naftifine
   D08245  Naftifine (INN)
BRITE hierarchy
Other DBs
CAS: 65472-88-0
PubChem: 96024933
ChEBI: 7451
ChEMBL: CHEMBL626
DrugBank: DB00735
LigandBox: D08245
NIKKAJI: J19.990G J244.941B
LinkDB All DBs
KCF data Show

ATOM        22
            1   C8x C    18.1300  -19.3200
            2   C8x C    18.1300  -20.7200
            3   C8x C    19.3200  -21.4200
            4   C8y C    20.5800  -20.7200
            5   C8y C    20.5800  -19.3200
            6   C8x C    19.3200  -18.6200
            7   C8x C    21.7700  -21.4200
            8   C8x C    22.9600  -20.7200
            9   C8x C    22.9600  -19.3200
            10  C8y C    21.7700  -18.6200
            11  C1b C    21.7700  -17.2200
            12  N1c N    22.9600  -16.5200
            13  C1b C    24.1500  -17.2200
            14  C1a C    22.9600  -15.1200
            15  C2b C    25.3400  -16.5200
            16  C2b C    26.5300  -17.2200
            17  C8y C    27.7200  -16.5200
            18  C8x C    28.9100  -17.2200
            19  C8x C    30.1700  -16.5200
            20  C8x C    30.1700  -15.1200
            21  C8x C    28.9800  -14.4200
            22  C8x C    27.7200  -15.1200
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 1
            15   12  14 1
            16   13  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 2
            24   17  22 1

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