| Entry |
|
|---|
| Name |
Olprinone (INN) |
|---|
| Formula |
C14H10N4O
|
|---|
| Exact mass |
250.0855
|
|---|
| Mol weight |
250.26
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01757 Amrinone type cardiotonic
DG01507 Phosphodiesterase III inhibitor
DG01757 Amrinone type cardiotonic
|
|---|
| Remark |
| Product (DG01396): | D02042<JP> |
|
|---|
| Efficacy |
Cardiotonic, Phosphodiesterase 3 inhibitor |
|---|
| Comment |
Amrinone derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01757 Amrinone type cardiotonic
DG01396 Olprinone
D08294 Olprinone
DG01507 Phosphodiesterase III inhibitor
DG01757 Amrinone type cardiotonic
DG01396 Olprinone
D08294 Olprinone
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Phosphodiesterases
PDE3
D08294 Olprinone (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01757 Amrinone type cardiotonic
DG01396 Olprinone
DG01507 Phosphodiesterase III inhibitor
DG01757 Amrinone type cardiotonic
DG01396 Olprinone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 19
1 C8y C 20.9300 -17.6400
2 C8y C 20.9300 -19.0400
3 N4x N 22.1200 -19.7400
4 C8y C 23.3100 -19.0400
5 C8y C 23.3100 -17.6400
6 C8x C 22.1200 -16.9400
7 O5x O 19.6700 -19.7400
8 C1a C 24.5700 -19.7400
9 C3b C 19.6700 -16.9400
10 N3a N 18.4800 -16.2400
11 C8y C 24.5700 -16.9400
12 C8x C 25.7600 -17.6400
13 N4y N 26.9500 -16.9400
14 C8y C 26.9500 -15.5400
15 C8x C 25.7600 -14.8400
16 C8x C 24.5700 -15.5400
17 C8x C 28.2800 -17.3600
18 C8x C 29.1200 -16.2400
19 N5x N 28.2800 -15.1200
BOND 21
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 2 7 2
8 4 8 1
9 1 9 1
10 9 10 3
11 5 11 1
12 11 12 2
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 2
17 11 16 1
18 13 17 1
19 17 18 2
20 18 19 1
21 14 19 2
|
|---|
