| Entry |
|
|---|
| Name |
Pethidine (INN);
Meperidine;
Pethidine DBL (TN) |
|---|
| Formula |
C15H21NO2
|
|---|
| Exact mass |
247.1572
|
|---|
| Mol weight |
247.33
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
| Product (DG00816): | D01383<JP/US> |
|
|---|
| Efficacy |
Analgesic (narcotic), Opioid receptor agonist |
|---|
| Comment |
Synthesis opioid
Phenylpiperidine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AB Phenylpiperidine derivatives
N02AB02 Pethidine
D08343 Pethidine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00816 Pethidine
D08343 Pethidine
Analgesic
DG01984 Opioid analgesics
DG00816 Pethidine
D08343 Pethidine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D08343 Pethidine (INN)
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Control Act Article 2 Table 1 (76 substances)
D08343
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00816 Pethidine
Analgesic
DG01984 Opioid analgesics
DG00816 Pethidine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 18
1 C8x C 25.1300 -16.0300
2 C8y C 25.1300 -17.4300
3 C8x C 26.3200 -18.1300
4 C8x C 27.5100 -17.4300
5 C8x C 27.5100 -16.0300
6 C8x C 26.3200 -15.3300
7 C1z C 23.8700 -18.1300
8 C1x C 22.6800 -17.5000
9 C1x C 21.4900 -18.2000
10 N1y N 21.4900 -19.6000
11 C1x C 22.6800 -20.2300
12 C1x C 23.8700 -19.5300
13 C1a C 20.2300 -20.3000
14 C7a C 24.5700 -19.3900
15 O7a O 26.0400 -19.3900
16 O6a O 23.8700 -20.5800
17 C1b C 26.6700 -20.5800
18 C1a C 28.1400 -20.5800
BOND 19
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 7 12 1
14 10 13 1
15 7 14 1
16 14 15 1
17 14 16 2
18 15 17 1
19 17 18 1
|
|---|
