| Entry |
|
|---|
| Name |
Pheniramine (INN) |
|---|
| Formula |
C16H20N2
|
|---|
| Exact mass |
240.1626
|
|---|
| Mol weight |
240.34
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Comment |
Pheniramine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA16 Pheniramine
D08355 Pheniramine (INN)
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AB Substituted alkylamines
R06AB05 Pheniramine
D08355 Pheniramine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Pheniramine
D08355 Pheniramine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01100 Pheniramine
D08355 Pheniramine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D08355 Pheniramine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01100 Pheniramine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 18
1 C8x C 27.8600 -19.3900
2 C8x C 27.8600 -20.7900
3 C8x C 26.6700 -21.4900
4 C8x C 25.4100 -20.7900
5 C8y C 25.4100 -19.3900
6 N5x N 26.6700 -18.6900
7 C1c C 24.2200 -18.6900
8 C8y C 22.9600 -19.3900
9 C1b C 24.2200 -17.2900
10 C8x C 22.9600 -20.7900
11 C8x C 21.7700 -21.4900
12 C8x C 20.5100 -20.7900
13 C8x C 20.5100 -19.3900
14 C8x C 21.7700 -18.6900
15 C1b C 25.4100 -16.5900
16 N1c N 25.4100 -15.1200
17 C1a C 26.6700 -14.4200
18 C1a C 24.2200 -14.4200
BOND 19
1 10 11 1
2 11 12 2
3 12 13 1
4 13 14 2
5 14 8 1
6 9 15 1
7 5 7 1
8 15 16 1
9 16 17 1
10 7 8 1
11 16 18 1
12 1 2 2
13 7 9 1
14 2 3 1
15 3 4 2
16 4 5 1
17 5 6 2
18 6 1 1
19 8 10 2
|
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