| Entry |
|
|---|
| Name |
Pirlindole (INN);
Pyrazidol (TN) |
|---|
| Formula |
C15H18N2
|
|---|
| Exact mass |
226.1470
|
|---|
| Mol weight |
226.32
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant, Monoamine oxidase A (MAO-A) inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa00260 | Glycine, serine and threonine metabolism |
| hsa00330 | Arginine and proline metabolism |
| hsa00982 | Drug metabolism - cytochrome P450 |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
DG01277 Pirlindole
D08392 Pirlindole
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Amine oxidases
MAOA
D08392 Pirlindole (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01558 Monoamine oxidase A inhibitor
DG01277 Pirlindole
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 17
1 C8y C 24.8500 -20.3700
2 C8x C 24.8500 -21.7700
3 C8x C 26.0400 -22.4700
4 C8y C 27.2300 -21.7700
5 C8y C 27.2300 -20.3700
6 C8x C 26.0400 -19.6700
7 N4y N 28.5600 -22.1900
8 C8y C 29.4000 -21.0700
9 C8y C 28.5600 -19.9500
10 C1y C 30.8000 -21.0700
11 C1a C 23.6600 -19.6700
12 C1x C 29.3300 -18.6200
13 C1x C 31.5000 -19.8100
14 C1x C 30.7300 -18.6200
15 C1x C 29.3300 -23.4500
16 C1x C 30.7300 -23.4500
17 N1x N 31.4300 -22.2600
BOND 20
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 2
10 5 9 1
11 8 10 1
12 1 11 1
13 12 9 1
14 10 13 1
15 13 14 1
16 12 14 1
17 7 15 1
18 15 16 1
19 16 17 1
20 17 10 1
|
|---|
