| Entry |
|
|---|
| Name |
Quinagolide hydrochloride (BAN);
Norprolac (TN) |
|---|
| Formula |
C20H33N3O3S. HCl
|
|---|
| Exact mass |
431.2009
|
|---|
| Mol weight |
432.02
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG01964 Ergot alkaloid
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihyperprolactinemia, Dopamine D2 receptor agonist |
|---|
| Comment |
Prolactin inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G02 OTHER GYNECOLOGICALS
G02C OTHER GYNECOLOGICALS
G02CB Prolactine inhibitors
G02CB04 Quinagolide
D08457 Quinagolide hydrochloride (BAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG00454 Quinagolide
D08457 Quinagolide hydrochloride
DG01964 Ergot alkaloid
DG00454 Quinagolide
D08457 Quinagolide hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D08457 Quinagolide hydrochloride (BAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG00454 Quinagolide
DG01964 Ergot alkaloid
DG00454 Quinagolide
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 28
1 C8x C 18.2000 -17.5700
2 C8x C 18.2000 -18.9700
3 C8x C 19.4600 -19.6700
4 C8y C 20.6500 -18.9700
5 C8y C 20.6500 -17.5700
6 C8y C 19.4600 -16.8700
7 C1x C 21.8400 -19.6700
8 C1y C 23.1000 -18.9700
9 C1y C 23.1000 -17.5700
10 C1x C 21.8400 -16.8700
11 N1y N 24.2900 -19.6700
12 C1x C 25.4800 -18.9700
13 C1y C 25.4800 -17.5700
14 C1x C 24.2900 -16.8700
15 O1a O 19.4600 -15.5400
16 C1b C 24.2900 -21.0700
17 C1b C 25.4800 -21.8400
18 C1a C 26.7400 -21.1400
19 N1b N 26.6700 -16.8700
20 S4a S 26.6700 -15.5400
21 N1c N 28.0700 -15.4700
22 C1b C 28.7700 -16.7300
23 C1b C 28.7700 -14.2800
24 C1a C 30.1700 -14.2800
25 C1a C 30.1700 -16.7300
26 O3c O 26.6700 -14.0000
27 O3c O 25.2700 -15.4700
28 X Cl 32.4100 -19.8800
BOND 29
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 9 14 1
17 6 15 1
18 11 16 1
19 16 17 1
20 17 18 1
21 19 20 1
22 20 21 1
23 21 22 1
24 21 23 1
25 23 24 1
26 22 25 1
27 20 26 2
28 20 27 2
29 13 19 1 #Down
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