| Entry |
|
|---|
| Name |
Rosiglitazone (INN);
Gaudil (TN) |
|---|
| Formula |
C18H19N3O3S
|
|---|
| Exact mass |
357.1147
|
|---|
| Mol weight |
357.43
|
|---|
| Structure |
|
|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, Peroxisome proliferator-activated receptor (PPAR) gamma agonist |
|---|
| Comment |
Thiazolidinedione derivative
|
|---|
| Target |
|
|---|
| Pathway |
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|---|
| Interaction |
|
|---|
| Structure map |
| map07222 | Peroxisome proliferator-activated receptor (PPAR) agonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BG Thiazolidinediones
A10BG02 Rosiglitazone
D08491 Rosiglitazone (INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01683 Thiazolidinedione
DG00116 Rosiglitazone
D08491 Rosiglitazone
DG02044 Hypoglycemic agent
DG01683 Thiazolidinedione
DG00116 Rosiglitazone
D08491 Rosiglitazone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C3 (PPARG)
D08491 Rosiglitazone (INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01683 Thiazolidinedione
DG00116 Rosiglitazone
DG02044 Hypoglycemic agent
DG01683 Thiazolidinedione
DG00116 Rosiglitazone
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C1y C 29.0500 -16.1000
2 C1b C 27.8600 -15.4700
3 S2x S 30.3800 -15.6800
4 C5x C 29.0500 -17.5700
5 C8y C 26.6000 -16.1000
6 C5x C 31.2200 -16.8000
7 N1x N 30.3800 -17.9900
8 O5x O 27.9300 -18.4100
9 C8x C 25.4100 -15.4700
10 C8x C 26.6000 -17.5700
11 O5x O 32.6200 -16.8000
12 C8x C 24.2200 -16.1000
13 C8x C 25.4100 -18.2000
14 C8y C 24.2200 -17.5700
15 O2a O 22.9600 -18.2000
16 C1b C 21.7700 -17.5700
17 C1b C 20.5800 -18.2000
18 N1c N 19.3900 -17.5700
19 C8y C 18.1300 -18.2000
20 C1a C 19.3900 -16.1000
21 C8x C 18.1300 -19.6700
22 N5x N 16.9400 -17.5700
23 C8x C 16.9400 -20.3700
24 C8x C 15.7500 -18.2700
25 C8x C 15.7500 -19.6700
BOND 27
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 1
7 4 8 2
8 5 9 2
9 5 10 1
10 6 11 2
11 9 12 1
12 10 13 2
13 12 14 2
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 18 20 1
20 19 21 1
21 19 22 2
22 21 23 2
23 22 24 1
24 23 25 1
25 6 7 1
26 13 14 1
27 24 25 2
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