KEGG   DRUG: SultoprideHelp
Entry
D08549                      Drug                                   

Name
Sultopride (INN)
Formula
C17H26N2O4S
Exact mass
354.1613
Mol weight
354.4643
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01941  Benzamide antipsychotic
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
Remark
Same as: C11708
ATC code: N05AL02
Chemical structure group: DG00900
Product (DG00900): D02208<JP>
Efficacy
Antipsychotic, Neuroleptic, Dopamine D2 receptor antagonist
Comment
Benzamide derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Structure map
map07213  Dopamine receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AL Benzamides
     N05AL02 Sultopride
      D08549  Sultopride (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D08549  Sultopride (INN)
BRITE hierarchy
Other DBs
CAS: 53583-79-2
PubChem: 96025234
ChEBI: 9356
ChEMBL: CHEMBL277945
DrugBank: DB00391
LigandBox: D08549
NIKKAJI: J10.063C
LinkDB All DBs
KCF data Show

ATOM        24
            1   S4a S    11.7600  -21.2800
            2   C1b C    10.5700  -21.9800
            3   O3c O    12.4600  -22.5400
            4   O3c O    11.0600  -20.0900
            5   C8y C    12.9500  -20.5800
            6   C8x C    12.9500  -19.1800
            7   C8x C    14.2100  -18.4800
            8   C8x C    14.2100  -21.2800
            9   C8y C    15.4000  -20.5800
            10  C8y C    15.4000  -19.1800
            11  O2a O    16.5900  -18.4800
            12  C5a C    16.5900  -21.2800
            13  N1b N    17.8500  -20.5800
            14  C1b C    19.0400  -21.2800
            15  O5a O    16.5900  -22.6800
            16  C1a C    16.5900  -17.0800
            17  C1a C     9.3100  -21.2800
            18  C1y C    20.2581  -20.5899
            19  N1y N    21.3786  -21.3805
            20  C1x C    22.4727  -20.5554
            21  C1x C    22.0262  -19.2598
            22  C1x C    20.6560  -19.2842
            23  C1b C    21.3297  -22.7491
            24  C1a C    22.6385  -23.4393
BOND        25
            1    13  12 1
            2    12   9 1
            3     1   4 2
            4     5   6 2
            5     6   7 1
            6    14  13 1
            7     7  10 2
            8     9   8 2
            9     8   5 1
            10    1   5 1
            11    1   2 1
            12   12  15 2
            13    1   3 2
            14    9  10 1
            15   10  11 1
            16   11  16 1
            17    2  17 1
            18   14  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   18  22 1
            24   19  23 1
            25   23  24 1

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