| Entry |
|
|---|
| Name |
Iclaprim mesylate (USAN) |
|---|
| Formula |
C19H22N4O3. CH4SO3
|
|---|
| Exact mass |
450.1573
|
|---|
| Mol weight |
450.51
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01581 Trimethoprim antibacterial
|
|---|
| Remark |
|
|---|
| Efficacy |
Antibacterial, Folic acid biosynthesis inhibitor |
|---|
| Target |
dihydrofolate reductase [KO: K13938] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01E SULFONAMIDES AND TRIMETHOPRIM
J01EA Trimethoprim and derivatives
J01EA03 Iclaprim
D08563 Iclaprim mesylate (USAN)
Drug groups [BR:br08330]
Antibacterial
DG01581 Trimethoprim antibacterial
DG00596 Iclaprim
D08563 Iclaprim mesylate
Antimicrobials [BR:br08307]
Antibacterials
Folic acid biosynthesis inhibitor
Trimethoprim
D08563 Iclaprim mesylate (USAN)
Drug groups [BR:br08330]
Antibacterial
DG01581 Trimethoprim antibacterial
DG00596 Iclaprim
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Folic acid biosynthesis inhibitor
Trimethoprim
DG00596 Iclaprim
|
|---|
| Other DBs |
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| LinkDB |
|
|---|
| KCF data |
ATOM 31
1 C8y C 23.0300 -25.2000
2 C1b C 24.2200 -25.9000
3 C8x C 21.8400 -25.9000
4 C8y C 23.0300 -23.8000
5 C8y C 25.4100 -25.2000
6 C8y C 20.5800 -25.2000
7 C8y C 21.8400 -23.1000
8 C8y C 26.6700 -25.9000
9 C8x C 25.4100 -23.7300
10 C8y C 20.5800 -23.8000
11 O2a O 19.3900 -25.9000
12 N5x N 27.8600 -25.2000
13 N1a N 26.6700 -27.3000
14 N5x N 26.6700 -23.0300
15 O2a O 19.3900 -23.1700
16 C1a C 18.2000 -25.1300
17 C8y C 27.8600 -23.7300
18 C1a C 19.3900 -21.7000
19 N1a N 29.0500 -23.0300
20 C2x C 24.2200 -23.1000
21 C2x C 24.2200 -21.7000
22 C1y C 23.1000 -21.0000
23 O2x O 21.8400 -21.7000
24 C1y C 23.1000 -19.6000
25 C1x C 23.8700 -18.4100
26 C1x C 22.4700 -18.4100
27 S4a S 34.2300 -23.6600
28 O1d O 34.2197 -25.0600
29 O1d O 34.2449 -22.2626
30 C1a C 32.8301 -23.6474
31 O1d O 35.6299 -23.6726
BOND 33
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 3 6 2
6 4 7 1
7 5 8 2
8 5 9 1
9 6 10 1
10 6 11 1
11 8 12 1
12 8 13 1
13 9 14 2
14 10 15 1
15 11 16 1
16 12 17 2
17 15 18 1
18 17 19 1
19 7 10 2
20 14 17 1
21 4 20 1
22 20 21 2
23 21 22 1
24 22 23 1
25 7 23 1
26 22 24 1
27 24 25 1
28 25 26 1
29 26 24 1
30 27 28 2
31 27 29 2
32 27 30 1
33 27 31 1
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