| Entry |
|
|---|
| Name |
Tiapride (INN);
Tiapridal (TN) |
|---|
| Formula |
C15H24N2O4S
|
|---|
| Exact mass |
328.1457
|
|---|
| Mol weight |
328.43
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01941 Benzamide antipsychotic
|
|---|
| Remark |
| Product (DG00901): | D01522<JP> |
|
|---|
| Efficacy |
Neuroleptic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Benzamide derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AL Benzamides
N05AL03 Tiapride
D08590 Tiapride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00901 Tiapride
D08590 Tiapride
DG03200 Antipsychotic agent
DG01941 Benzamide antipsychotic
DG00901 Tiapride
D08590 Tiapride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D08590 Tiapride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00901 Tiapride
DG03200 Antipsychotic agent
DG01941 Benzamide antipsychotic
DG00901 Tiapride
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 C8x C 8.4700 -27.0900
2 C8y C 8.4700 -28.4900
3 C8x C 9.6824 -29.1900
4 C8y C 10.8949 -28.4900
5 C8y C 10.8949 -27.0900
6 C8x C 9.6824 -26.3900
7 C5a C 12.1260 -29.2010
8 N1b N 13.3312 -28.5053
9 O5a O 12.1257 -30.5899
10 C1b C 14.5135 -29.1881
11 C1b C 15.7075 -28.4988
12 N1c N 16.8954 -29.1848
13 C1b C 18.0865 -28.4971
14 C1b C 16.8955 -30.5898
15 C1a C 18.0888 -31.2789
16 C1a C 19.2759 -29.1839
17 O2a O 12.1260 -26.3790
18 C1a C 12.1260 -24.9790
19 S4a S 7.2576 -29.1900
20 C1a C 6.0451 -29.8900
21 O3c O 7.9576 -30.4024
22 O3c O 6.5576 -27.9776
BOND 22
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 7 9 2
10 8 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 12 14 1
15 14 15 1
16 13 16 1
17 5 17 1
18 17 18 1
19 2 19 1
20 19 20 1
21 19 21 2
22 19 22 2
|
|---|
