KEGG   DRUG: TiaprideHelp
Entry
D08590                      Drug                                   

Name
Tiapride (INN);
Tiapridal (TN)
Formula
C15H24N2O4S
Exact mass
328.1457
Mol weight
328.4271
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01941  Benzamide antipsychotic
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
Remark
ATC code: N05AL03
Chemical structure group: DG00901
Product (DG00901): D01522<JP>
Efficacy
Neuroleptic, Dopamine D2 receptor antagonist
Comment
Benzamide derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AL Benzamides
     N05AL03 Tiapride
      D08590  Tiapride (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D08590  Tiapride (INN)
BRITE hierarchy
Other DBs
CAS: 51012-32-9
PubChem: 96025274
ChEMBL: CHEMBL84158
LigandBox: D08590
NIKKAJI: J11.205D
LinkDB All DBs
KCF data Show

ATOM        22
            1   C8x C     8.4700  -27.0900
            2   C8y C     8.4700  -28.4900
            3   C8x C     9.6824  -29.1900
            4   C8y C    10.8949  -28.4900
            5   C8y C    10.8949  -27.0900
            6   C8x C     9.6824  -26.3900
            7   C5a C    12.1260  -29.2010
            8   N1b N    13.3312  -28.5053
            9   O5a O    12.1257  -30.5899
            10  C1b C    14.5135  -29.1881
            11  C1b C    15.7075  -28.4988
            12  N1c N    16.8954  -29.1848
            13  C1b C    18.0865  -28.4971
            14  C1b C    16.8955  -30.5898
            15  C1a C    18.0888  -31.2789
            16  C1a C    19.2759  -29.1839
            17  O2a O    12.1260  -26.3790
            18  C1a C    12.1260  -24.9790
            19  S4a S     7.2576  -29.1900
            20  C1a C     6.0451  -29.8900
            21  O3c O     7.9576  -30.4024
            22  O3c O     6.5576  -27.9776
BOND        22
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     7   9 2
            10    8  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   12  14 1
            15   14  15 1
            16   13  16 1
            17    5  17 1
            18   17  18 1
            19    2  19 1
            20   19  20 1
            21   19  21 2
            22   19  22 2

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