| Entry |
|
|---|
| Name |
Varenicline (INN) |
|---|
| Formula |
C13H13N3
|
|---|
| Exact mass |
211.1109
|
|---|
| Mol weight |
211.26
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
Unclassified
DG01715 Drugs for nicotine dependence
|
|---|
| Remark |
| Product (DG00995): | D06282<JP/US> |
|
|---|
| Efficacy |
Smoking cessation adjunct, Selective nicotinic acetylcholine receptor modulator |
|---|
| Comment |
Nicotine withdrawal
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07B DRUGS USED IN ADDICTIVE DISORDERS
N07BA Drugs used in nicotine dependence
N07BA03 Varenicline
D08669 Varenicline (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA28 Varenicline
D08669 Varenicline (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
DG00995 Varenicline
D08669 Varenicline
Unclassified
DG01715 Drugs for nicotine dependence
DG00995 Varenicline
D08669 Varenicline
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRNA4/CHRNB2
D08669 Varenicline (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
DG00995 Varenicline
Unclassified
DG01715 Drugs for nicotine dependence
DG00995 Varenicline
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 16
1 C8y C 21.3615 -14.3766
2 C1y C 20.2443 -13.4688
3 C1x C 18.9176 -13.8180
4 N1x N 18.3590 -15.0748
5 C8y C 21.3615 -15.7731
6 C1x C 18.9176 -16.2618
7 C1y C 20.2443 -16.5411
8 C8x C 22.5484 -16.4015
9 C8y C 23.7354 -15.7731
10 C8y C 23.7354 -14.3766
11 C8x C 22.5484 -13.6783
12 N5x N 24.9224 -16.4015
13 C8x C 26.1095 -15.7731
14 C8x C 26.1095 -14.3766
15 N5x N 24.9224 -13.6783
16 C1x C 19.6159 -15.0050
BOND 19
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 5 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 1 11 2
13 9 12 1
14 12 13 2
15 13 14 1
16 14 15 2
17 10 15 1
18 2 16 1
19 7 16 1
|
|---|
