KEGG   DRUG: Besifloxacin hydrochlorideHelp
Entry
D08872                      Drug                                   

Name
Besifloxacin hydrochloride (USAN);
Besivance (TN)
Product
Formula
C19H21ClFN3O3. HCl
Exact mass
429.1022
Mol weight
430.3007
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
ATC code: S01AE08
Product: D08872<US>
Efficacy
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470]
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE08 Besifloxacin
      D08872  Besifloxacin hydrochloride (USAN) <US>
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Besifloxacin
    D08872  Besifloxacin hydrochloride (USAN)
Antiinfectives [br08350.html]
 Antibacterials
  D08872
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D08872
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D08872
BRITE hierarchy
Other DBs
CAS: 405165-61-9
PubChem: 96025555
ChEMBL: CHEMBL1201761
LigandBox: D08872
LinkDB All DBs
KCF data Show

ATOM        28
            1   C8y C    23.5900  -15.6100
            2   C8y C    23.5900  -17.0100
            3   C8y C    24.7800  -17.7100
            4   C8y C    26.0400  -17.0100
            5   C8y C    26.0400  -15.6100
            6   C8x C    24.7800  -14.9100
            7   N4y N    27.2300  -17.7100
            8   C8x C    28.4200  -17.0100
            9   C8y C    28.4200  -15.6100
            10  C8y C    27.2300  -14.9100
            11  X   F    22.4000  -14.9100
            12  O5x O    27.2300  -13.5100
            13  C6a C    29.6100  -14.9100
            14  O6a O    30.8000  -15.6100
            15  O6a O    29.6100  -13.5100
            16  C1y C    27.2300  -19.1100
            17  C1x C    27.9300  -20.3000
            18  C1x C    26.5300  -20.3000
            19  X   Cl   24.7628  -19.1099
            20  C1y C    20.1000  -18.3247
            21  C1x C    21.1967  -17.4610
            22  N1y N    22.5621  -17.7724
            23  C1x C    23.1640  -19.0256
            24  C1x C    20.1000  -19.7337
            25  C1x C    22.5630  -20.2929
            26  C1x C    21.1967  -20.6045
            27  N1a N    18.8385  -17.7124
            28  X   Cl   33.6000  -17.5000
BOND        30
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    1  11 1
            13   10  12 2
            14    9  13 1
            15   13  14 1
            16   13  15 2
            17    7  16 1
            18   16  17 1
            19   16  18 1
            20   17  18 1
            21    3  19 1
            22   22  23 1
            23   20  24 1
            24   23  25 1
            25   21  22 1
            26   24  26 1
            27   20  21 1
            28   25  26 1
            29    2  22 1
            30   20  27 1 #Up

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