KEGG   DRUG: BetrixabanHelp
Entry
D08873                      Drug                                   

Name
Betrixaban (USAN)
Product
Formula
C23H22ClN5O3
Exact mass
451.1411
Mol weight
451.9055
Structure
Mol fileKCF fileDB search
Class
Cardiovascular agent
 DG01662  Factor Xa inhibitor
 DG01950  Antithrombotic agent
  DG01662  Factor Xa inhibitor
Remark
Product: D08873<US>
Efficacy
Antithrombotic, Factor Xa inhibitor
Comment
Prevention of deep vein thrombosis and pulmonary embolism after surgery
Target
F10 [HSA:2159] [KO:K01314]
  Pathway
hsa04610  Complement and coagulation cascades
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Immune system
   Complement and coagulation
    F10
     D08873  Betrixaban (USAN) <US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D08873
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D08873
BRITE hierarchy
Other DBs
CAS: 330942-05-7
PubChem: 96025556
ChEBI: 140421
ChEMBL: CHEMBL512351
LigandBox: D08873
LinkDB All DBs
KCF data Show

ATOM        32
            1   C8y C    15.6800  -12.5300
            2   C8x C    15.6800  -13.9300
            3   C8x C    16.8700  -14.6300
            4   C8y C    18.0600  -13.9300
            5   C8x C    18.0600  -12.5300
            6   C8x C    16.8700  -11.9000
            7   C2c C    14.4200  -11.9000
            8   N1c N    13.2300  -12.5300
            9   C5a C    19.2500  -14.6300
            10  N2a N    14.4200  -10.5000
            11  N1b N    20.4400  -14.0000
            12  C8y C    21.6300  -14.6300
            13  O5a O    19.2500  -16.0300
            14  C1a C    12.0441  -11.7860
            15  C1a C    13.2486  -13.9291
            16  C8x C    21.6114  -16.0291
            17  C8x C    22.9187  -16.6841
            18  C8y C    24.1046  -15.9401
            19  C8x C    24.0532  -14.5410
            20  C8y C    22.8159  -13.8860
            21  O2a O    25.3305  -16.5894
            22  C1a C    26.5231  -15.8415
            23  C5a C    22.8335  -12.4611
            24  O5a O    21.5152  -11.8003
            25  N1b N    23.9402  -11.7228
            26  C8y C    25.1637  -12.3700
            27  C8x C    25.1467  -13.7873
            28  C8x C    26.4544  -14.4416
            29  C8y C    27.5699  -13.6968
            30  C8x C    27.5869  -12.2795
            31  N5x N    26.3492  -11.6253
            32  X   Cl   28.8181  -14.3736
BOND        34
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     4   9 1
            10    7  10 2
            11    9  11 1
            12   11  12 1
            13    9  13 2
            14    8  14 1
            15    8  15 1
            16   12  16 2
            17   16  17 1
            18   17  18 2
            19   18  19 1
            20   19  20 2
            21   12  20 1
            22   18  21 1
            23   21  22 1
            24   20  23 1
            25   23  24 2
            26   23  25 1
            27   25  26 1
            28   26  27 2
            29   27  28 1
            30   28  29 2
            31   29  30 1
            32   30  31 2
            33   26  31 1
            34   29  32 1

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