KEGG   DRUG: Ceftaroline fosamilHelp
Entry
D08884                      Drug                                   

Name
Ceftaroline fosamil (USAN/INN);
Teflaro (TN)
Product
Formula
C22H21N8O8PS4. C2H4O2. H2O
Exact mass
762.042
Mol weight
762.7519
Structure
Mol fileKCF fileDB search
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01804  Oxyimino beta-lactam
Remark
ATC code: J01DI02
Product: D08884<US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DI Other cephalosporins and penems
     J01DI02 Ceftaroline fosamil
      D08884  Ceftaroline fosamil (USAN/INN) <US>
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Ceftaroline fosamil
    D08884  Ceftaroline fosamil (USAN/INN)
Antiinfectives [br08350.html]
 Antibacterials
  D08884
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D08884
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D08884
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D08884
BRITE hierarchy
Other DBs
CAS: 866021-48-9
PubChem: 96025567
ChEBI: 70714
ChEMBL: CHEMBL3544973
LigandBox: D08884
LinkDB All DBs
KCF data Show

ATOM        48
            1   C1y C    20.9508  -15.6226
            2   N1y N    20.9508  -17.0237
            3   C2y C    22.1418  -17.7243
            4   C2y C    23.3327  -17.0237
            5   C1x C    23.3327  -15.6226
            6   S2x S    22.1418  -14.9221
            7   C1y C    19.5497  -15.6226
            8   C5x C    19.5497  -17.0237
            9   N1b N    18.2887  -14.9221
            10  C5a C    17.0977  -15.6226
            11  O5a O    17.0977  -17.0237
            12  O5x O    18.2887  -17.7243
            13  C2c C    15.9068  -14.9221
            14  S2a S    24.5937  -17.7243
            15  C8y C    14.6458  -15.6226
            16  N5x N    13.5949  -14.7820
            17  S2x S    12.4040  -15.5526
            18  C8y C    12.8244  -16.9537
            19  N5x N    14.2254  -16.9537
            20  N2b N    15.9068  -13.5210
            21  C6a C    22.1418  -19.1254
            22  O6a O    23.3327  -19.8260 #-
            23  O6a O    20.8808  -19.8260
            24  N1b N    11.9837  -18.0746
            25  O2a O    17.0977  -12.8203
            26  C1b C    18.3168  -13.5111
            27  C1a C    19.4991  -12.8153
            28  P1b P    10.5826  -18.0746
            29  O1c O     9.1814  -18.0746
            30  O1c O    10.5826  -16.6734
            31  O1c O    10.5826  -19.4757
            32  C8y C    25.7905  -17.0069
            33  S2x S    27.0697  -17.5515
            34  C8x C    27.9831  -16.5030
            35  C8y C    27.2682  -15.3106
            36  N5x N    25.9131  -15.6219
            37  C8y C    27.8035  -14.0526
            38  C8x C    29.1928  -13.8833
            39  C8x C    29.7413  -12.5944
            40  N5y N    28.8993  -11.4750 #+
            41  C8x C    27.5099  -11.6444
            42  C8x C    26.9615  -12.9332
            43  C1a C    29.4480  -10.1856
            44  C6a C    31.7388  -18.7753
            45  O6a O    32.9522  -19.4759
            46  C1a C    30.5254  -19.4759
            47  O6a O    31.7388  -17.3743
            48  O0  O    35.3124  -16.1133
BOND        50
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16   13  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 1
            20   18  19 2
            21   15  19 1
            22   13  20 2
            23    3  21 1
            24   21  22 1
            25   21  23 2
            26   18  24 1
            27   20  25 1
            28   25  26 1
            29   26  27 1
            30   24  28 1
            31   28  29 1
            32   28  30 1
            33   28  31 2
            34   14  32 1
            35   32  33 1
            36   33  34 1
            37   34  35 2
            38   35  36 1
            39   32  36 2
            40   35  37 1
            41   37  38 2
            42   38  39 1
            43   39  40 2
            44   40  41 1
            45   41  42 2
            46   37  42 1
            47   40  43 1
            48   44  45 1
            49   44  46 1
            50   44  47 2

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