| Entry |
|
|---|
| Name |
Eglumegad (INN) |
|---|
| Formula |
C8H11NO4
|
|---|
| Exact mass |
185.0688
|
|---|
| Mol weight |
185.18
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antianxiety, Smoking cessation adjunct, Metabotropic glutamate receptor agonist |
|---|
| Comment |
Treatment of general anxiety disorders and smoking cessation
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Metabotropic glutamate receptor family
Glutamate (metabotropic)
GRM2
D08908 Eglumegad (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 13
1 C1y C 24.8282 -18.8616
2 C1y C 24.8282 -20.2647
3 C1z C 26.1627 -20.6983
4 C1x C 26.9874 -19.5632
5 C1x C 26.1627 -18.4280
6 C1y C 23.6131 -19.5632
7 C6a C 22.2324 -19.5632
8 O6a O 21.5308 -18.3481
9 O6a O 21.5308 -20.7783
10 C6a C 27.3778 -21.3999
11 N1a N 26.1627 -22.1014
12 O6a O 28.5801 -20.7054
13 O6a O 27.3777 -22.7902
BOND 14
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 1 6 1
7 2 6 1
8 6 7 1 #Up
9 7 8 1
10 7 9 2
11 3 10 1 #Up
12 3 11 1 #Down
13 10 12 1
14 10 13 2
|
|---|
