KEGG   DRUG: Inotuzumab ozogamicinHelp
Entry
D08933                      Drug                                   

Name
Inotuzumab ozogamicin (USAN/INN);
Inotuzumab ozogamicin (genetical recombination) (JAN);
Besponsa (TN)
Product
Formula
C6518H10002N1738O2036S42
Exact mass
146542.0817
Mol weight
146632.3115
Remark
Therapeutic category: 4239
ATC code: L01XC26
Product: D08933<JP/US>
Efficacy
Antineoplastic, DNA synthesis inhibitor, Anti-CD22 antibody
  Disease
B-cell precursor acute lymphoblastic leukemia [DS:H00001]
Comment
Antibody-drug conjugate
Target
CD22 [HSA:933] [KO:K06467]
  Pathway
hsa04514  Cell adhesion molecules (CAMs)
hsa04640  Hematopoietic cell lineage
hsa04662  B cell receptor signaling pathway
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XC Monoclonal antibodies
     L01XC26 Inotuzumab ozogamicin
      D08933  Inotuzumab ozogamicin (USAN/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   423  Antibiotics
    4239  Others
     D08933  Inotuzumab ozogamicin (USAN/INN); Inotuzumab ozogamicin (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Cell adhesion molecules: Ig superfamiy
   SIGLEC family
    CD22
     D08933  Inotuzumab ozogamicin (USAN/INN) <JP/US>
Antineoplastics [br08340.html]
 D08933
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D08933
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D08933
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D08933
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D08933
Pharmacogenomic biomarkers [br08341.html]
 Companion diagnostics
  D08933
BRITE hierarchy
Other DBs
CAS: 635715-01-4
PubChem: 96025616
LinkDB All DBs

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