| Entry |
|
|---|
| Name |
Ispronicline (INN/USAN) |
|---|
| Formula |
C14H22N2O
|
|---|
| Exact mass |
234.1732
|
|---|
| Mol weight |
234.34
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
|
|---|
| Efficacy |
Dementia therapeutic agent, Nicotinic acetylcholine receptor partial agonist |
|---|
| Comment |
Treatment of cognitive and memory disorders
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
D08935 Ispronicline
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRNA4/CHRNB2
D08935 Ispronicline (INN/USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 17
1 C8x C 21.4900 -15.2600
2 N5x N 21.4900 -16.6600
3 C8x C 22.7024 -17.3600
4 C8y C 23.9149 -16.6600
5 C8x C 23.9149 -15.2600
6 C8y C 22.7024 -14.5600
7 C2b C 25.1524 -17.3600
8 C2b C 26.3649 -16.6600
9 C1b C 27.5773 -17.3600
10 C1c C 28.7897 -16.6600
11 C1a C 30.0022 -17.3600
12 N1b N 28.7897 -15.2601
13 C1a C 27.5625 -14.5515
14 O2a O 22.7024 -13.1602
15 C1c C 21.4732 -12.4503
16 C1a C 20.2692 -13.1454
17 C1a C 21.4734 -11.0601
BOND 17
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 1
11 10 11 1
12 10 12 1 #Up
13 12 13 1
14 6 14 1
15 14 15 1
16 15 16 1
17 15 17 1
|
|---|
