KEGG   DRUG: Quarfloxin
Entry
D08981                      Drug                                   

Name
Quarfloxin (USAN)
Formula
C35H33FN6O3
Exact mass
604.2598
Mol weight
604.6733
Structure
Class
Other
 DG01529  Topoisomerase inhibitor
  DG01527  Topoisomerase II inhibitor
Efficacy
Antineoplastic, Topoisomerase II inhibitor
Target
TOP2 [HSA:7153 7155] [KO:K03164]
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Isomerases (EC5)
   DNA topoisomerase
    TOP2
     D08981  Quarfloxin (USAN)
Other DBs
CAS: 865311-47-3
PubChem: 96025664
ChEBI: 177533
ChEMBL: CHEMBL3989407
LigandBox: D08981
LinkDB
KCF data

ATOM        45
            1   C8x C    11.5289  -14.4601
            2   C8x C    11.5289  -15.8573
            3   C8x C    12.7389  -16.5559
            4   C8y C    13.9490  -15.8573
            5   C8y C    13.9490  -14.4601
            6   C8x C    12.7389  -13.7614
            7   C8x C    15.1590  -16.5559
            8   C8y C    16.3690  -15.8573
            9   C8y C    16.3690  -14.4601
            10  C8x C    15.1590  -13.7614
            11  O2x O    17.5791  -16.5559
            12  C8y C    18.7892  -15.8573
            13  C8y C    18.7892  -14.4601
            14  N4y N    17.5791  -13.7614
            15  C8y C    19.9992  -16.5559
            16  C8y C    21.2093  -15.8573
            17  C8x C    21.2093  -14.4601
            18  C8y C    19.9992  -13.7614
            19  C8y C    19.9992  -12.3642
            20  C8y C    18.7892  -11.6656
            21  C8x C    17.5791  -12.3642
            22  C5a C    18.7892  -10.2683
            23  N1b N    20.0033   -9.5674
            24  C1b C    21.1984  -10.2576
            25  C1b C    22.3824   -9.5740
            26  C1y C    23.5718  -10.2610
            27  N1y N    23.5785  -11.5849
            28  C1x C    25.0891  -11.9463
            29  C1x C    25.7899  -10.7326
            30  C1x C    24.8522   -9.6910
            31  N1y N    19.9992  -17.9531
            32  X   F    22.4419  -16.5693
            33  O5a O    17.5831   -9.5720
            34  O5x O    21.1964  -11.6729
            35  C1a C    22.6563  -12.7509
            36  C1x C    18.8577  -18.7825
            37  C1x C    19.2939  -20.1244
            38  C1y C    20.7049  -20.1243
            39  C1x C    21.1407  -18.7823
            40  C8y C    21.5152  -21.1698
            41  N5x N    20.9409  -22.3427
            42  C8x C    21.6399  -23.5525
            43  C8x C    23.0372  -23.5520
            44  N5x N    23.7333  -22.3455
            45  C8x C    23.0342  -21.1357
BOND        52
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12    8  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16    9  14 1
            17   12  15 2
            18   15  16 1
            19   16  17 2
            20   17  18 1
            21   13  18 2
            22   18  19 1
            23   19  20 1
            24   20  21 2
            25   14  21 1
            26   20  22 1
            27   22  23 1
            28   23  24 1
            29   24  25 1
            30   26  25 1 #Down
            31   26  27 1
            32   27  28 1
            33   28  29 1
            34   29  30 1
            35   26  30 1
            36   15  31 1
            37   16  32 1
            38   22  33 2
            39   19  34 2
            40   27  35 1
            41   31  36 1
            42   36  37 1
            43   37  38 1
            44   38  39 1
            45   31  39 1
            46   38  40 1
            47   40  41 2
            48   41  42 1
            49   42  43 2
            50   43  44 1
            51   44  45 2
            52   40  45 1

» Japanese version   » Back

DBGET integrated database retrieval system