KEGG   DRUG: Minodronic acid hydrate
Entry
D09198                      Drug                                   
Name
Minodronic acid hydrate (JAN);
Bonoteo (TN);
Recalbon (TN)
Formula
C9H12N2O7P2. H2O
Exact mass
340.0225
Mol weight
340.16
Structure
Class
Musculo-skeletal system agent
 DG03232  Osteoporosis agent
  DG01600  Bisphosphonate
Remark
Therapeutic category: 3999
Product: D09198<JP>
Efficacy
Antiresorptive, Osteoporosis agent, Farnesylpyrophosphate synthetase inhibitor
Comment
Bisphosphonate
Target
FDPS [HSA:2224] [KO:K00787]
  Pathway
hsa00900  Terpenoid backbone biosynthesis
Interaction
Structure map
map07047  Osteoporosis drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D09198  Minodronic acid hydrate (JAN)
Drug groups [BR:br08330]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   DG01600  Bisphosphonate
    D09198  Minodronic acid hydrate
Drug classes [BR:br08332]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   D09198  Minodronic acid hydrate
Target-based classification of drugs [BR:br08310]
 Enzymes
  Transferases (EC2)
   Alkyl/Aryl transferases
    FDPS
     D09198  Minodronic acid hydrate (JAN) <JP>
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09198
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09198
Other DBs
PubChem: 96025878
LigandBox: D09198
LinkDB
KCF data

ATOM        21
            1   C1d C    23.1352  -24.8855
            2   P1b P    24.3313  -25.5892
            3   P1b P    21.9390  -25.5892
            4   C1b C    23.1352  -23.4783
            5   C8y C    24.3313  -22.7747
            6   O1c O    25.5275  -24.8855
            7   O1c O    24.3313  -26.9964
            8   O1c O    25.5275  -26.2928
            9   O1c O    20.7428  -24.8855
            10  O1c O    21.9390  -26.9964
            11  O1c O    20.7428  -26.2928
            12  C8x C    25.6682  -23.1968
            13  N5x N    26.5126  -22.0710
            14  C8y C    25.6682  -20.9452
            15  N4y N    24.3313  -21.3674
            16  C8x C    25.9722  -19.5712
            17  C8x C    24.9342  -18.6209
            18  C8x C    23.5974  -19.0431
            19  C8x C    23.2934  -20.4171
            20  O1a O    23.1352  -26.2928
            21  O0  O    28.8400  -24.0800
BOND        21
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     4   5 1
            5     2   6 2
            6     2   7 1
            7     2   8 1
            8     3   9 2
            9     3  10 1
            10    3  11 1
            11    5  12 2
            12   12  13 1
            13   13  14 2
            14   14  15 1
            15    5  15 1
            16   14  16 1
            17   16  17 2
            18   17  18 1
            19   18  19 2
            20   15  19 1
            21    1  20 1

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