| Entry |
|
|---|
| Name |
Pozanicline tartrate (USAN) |
|---|
| Formula |
C11H16N2O. C4H6O6
|
|---|
| Exact mass |
342.1427
|
|---|
| Mol weight |
342.34
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Dementia therapeutic agent, Nicotinic acetylcholine receptor partial agonist |
|---|
| Comment |
Attention deficit/hyperactivity disorder (ADHD), dementia of the Alzheimer's type (AD)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
DG01288 Pozanicline
D09368 Pozanicline tartrate
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRNA4/CHRNB2
D09368 Pozanicline tartrate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
DG01288 Pozanicline
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C8y C 19.4197 -24.4214
2 C8x C 19.4197 -25.8249
3 C8x C 18.2268 -26.5266
4 C8x C 16.9636 -25.8249
5 N5x N 16.9636 -24.4214
6 C8y C 18.2268 -23.7196
7 O2a O 20.6127 -23.7196
8 C1b C 21.8057 -24.4214
9 C1y C 22.9986 -23.7196
10 C1x C 23.4197 -22.3863
11 C1x C 24.8232 -22.3863
12 C1x C 25.2442 -23.7196
13 N1x N 24.1214 -24.5617
14 C1a C 18.2268 -22.3161
15 C6a C 28.5425 -23.7196
16 O6a O 27.3270 -24.4214
17 C1c C 29.7726 -24.4298
18 C1c C 30.9679 -23.7395
19 C6a C 32.1553 -24.4250
20 O6a O 33.3465 -23.7370
21 O6a O 32.1555 -25.8298
22 O6a O 28.5426 -22.3301
23 O1a O 29.7727 -25.8298
24 O1a O 30.9679 -22.3303
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 1
9 9 8 1 #Down
10 10 11 1
11 11 12 1
12 12 13 1
13 13 9 1
14 10 9 1
15 6 14 1
16 15 16 1
17 15 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 19 21 2
22 15 22 2
23 17 23 1 #Up
24 18 24 1 #Up
|
|---|
