| Entry |
|
|---|
| Name |
Sivifene (USAN/INN) |
|---|
| Formula |
C19H14N4O6
|
|---|
| Exact mass |
394.0913
|
|---|
| Mol weight |
394.34
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01585 Estrogen receptor antagonist
DG01620 Tamoxifene-type antineoplastic
Hormonal agent
DG01619 Estrogen receptor antagonist/modulator
|
|---|
| Efficacy |
Antineoplastic |
|---|
| Comment |
Treatment of high-grade squamous intraepithelial lesions of the cervix and other neoplasms
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01585 Estrogen receptor antagonist
DG01620 Tamoxifene-type antineoplastic
D09380 Sivifene
Hormonal agent
DG01619 Estrogen receptor antagonist/modulator
D09380 Sivifene
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 C8x C 9.6600 -29.4700
2 C8y C 9.6600 -30.8700
3 C8x C 10.8724 -31.5700
4 C8x C 12.0849 -30.8700
5 C8y C 12.0849 -29.4700
6 C8x C 10.8724 -28.7700
7 C2c C 13.3160 -28.7590
8 C8y C 14.5212 -29.4547
9 C8x C 14.5216 -30.8696
10 C8x C 15.7342 -31.5693
11 C8y C 16.9465 -30.8689
12 C8x C 16.9460 -29.4539
13 C8x C 15.7334 -28.7543
14 O1a O 18.1547 -31.5660
15 O1a O 8.4476 -31.5700
16 N2b N 13.3157 -27.3701
17 N1b N 14.5162 -26.6766
18 C8y C 14.5161 -25.2702
19 C8y C 15.7089 -24.5812
20 C8x C 15.7085 -23.1812
21 C8y C 14.4959 -22.4815
22 C8x C 13.3032 -23.1705
23 C8x C 13.3035 -24.5705
24 N2b N 14.4956 -21.0700 #+
25 O3a O 13.2788 -20.3678
26 O3a O 15.9137 -20.1622 #-
27 N2b N 16.8949 -25.2657 #+
28 O3a O 18.2966 -24.3673 #-
29 O3a O 16.8953 -26.6698
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 11 14 1
16 2 15 1
17 7 16 2
18 16 17 1
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 18 23 1
26 21 24 1
27 24 25 2
28 24 26 1
29 19 27 1
30 27 28 1
31 27 29 2
|
|---|
