| Entry |
|
|---|
| Name |
Arhalofenate (USAN/INN) |
|---|
| Formula |
C19H17ClF3NO4
|
|---|
| Exact mass |
415.0798
|
|---|
| Mol weight |
415.79
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
|
|---|
| Efficacy |
Antidiabetic, Uricosuric, Peroxisome proliferator-activated receptor (PPAR) gamma agonist |
|---|
| Comment |
Treatment of type 2 diabetes, Treatment of hyperuricemica in patients with gout
|
|---|
| Target |
|
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| Pathway |
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| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
D09579 Arhalofenate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C3 (PPARG)
D09579 Arhalofenate (USAN/INN)
|
|---|
| Other DBs |
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| LinkDB |
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|---|
| KCF data |
ATOM 28
1 C8y C 13.2594 -14.4186
2 C8x C 13.2594 -15.8226
3 C8x C 14.4753 -16.5246
4 C8x C 15.6913 -15.8226
5 C8y C 15.6913 -14.4186
6 C8x C 14.4753 -13.7164
7 O2a O 16.9260 -13.7055
8 C1c C 18.1347 -14.4032
9 C7a C 19.3205 -13.7183
10 O7a O 20.5179 -14.4097
11 O6a O 19.3205 -12.3126
12 C8y C 18.1351 -15.8222
13 C1b C 21.7092 -13.7217
14 C1b C 22.9038 -14.4114
15 N1b N 24.0967 -13.7226
16 C5a C 25.2905 -14.4119
17 C1a C 26.4839 -13.7228
18 O5a O 25.2907 -15.8224
19 C1d C 12.0434 -13.7164
20 X F 10.8273 -13.0144
21 C8x C 16.8956 -16.5387
22 C8x C 16.8963 -17.9427
23 C8y C 18.1126 -18.6441
24 C8x C 19.3522 -17.9277
25 C8x C 19.3515 -16.5236
26 X Cl 18.1132 -20.0349
27 X F 12.7432 -12.5044
28 X F 11.3436 -14.9286
BOND 29
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1 #Up
10 9 10 1
11 9 11 2
12 8 12 1
13 10 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 16 18 2
19 1 19 1
20 19 20 1
21 12 21 1
22 21 22 2
23 22 23 1
24 23 24 2
25 24 25 1
26 12 25 2
27 23 26 1
28 19 27 1
29 19 28 1
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