| Entry |
|
|---|
| Name |
Dilmapimod tosylate (USAN) |
|---|
| Formula |
C23H19F3N4O3. C7H8O3S
|
|---|
| Exact mass |
628.1603
|
|---|
| Mol weight |
628.62
|
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| Structure |
|
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| Remark |
|
|---|
| Efficacy |
Anti-inflammatory, Mitogen-activated protein kinase inhibitor |
|---|
| Comment |
COPD, rheumatoid arthritis, atherosclerosis, neuropathic pain, acute lung injury (ALI), acute respiratory distress syndrome (ARDS)
|
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| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Protein kinases
Serine/threonine kinases
CMGC group
P38
D09603 Dilmapimod tosylate (USAN)
|
|---|
| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 44
1 N4y N 21.2800 -28.3500
2 C8y C 21.2800 -29.7500
3 C8x C 22.4700 -30.4500
4 C8x C 23.7300 -29.7500
5 C8y C 23.7300 -28.3500
6 C8y C 22.4700 -27.6500
7 C8y C 24.9200 -27.6500
8 N5x N 24.9200 -26.2500
9 C8y C 23.7300 -25.5500
10 N5x N 22.4700 -26.2500
11 C8y C 20.0900 -27.6500
12 O5x O 20.0900 -30.4500
13 C8y C 26.1100 -28.3500
14 N1b N 23.7300 -24.1500
15 C1c C 24.9200 -23.4500
16 C1b C 26.1100 -24.1500
17 C1b C 24.9200 -22.0500
18 O1a O 26.1100 -21.3500
19 O1a O 27.3000 -23.4500
20 C8y C 26.1100 -29.7500
21 C8x C 27.3700 -30.4500
22 C8y C 28.5600 -29.7500
23 C8x C 28.5600 -28.3500
24 C8x C 27.3700 -27.6500
25 C1a C 24.9200 -30.4500
26 X F 29.7500 -30.4500
27 C8y C 20.0900 -26.2500
28 C8x C 18.8300 -25.5500
29 C8x C 17.6400 -26.2500
30 C8x C 17.6400 -27.6500
31 C8y C 18.8300 -28.3500
32 X F 18.8300 -29.7500
33 X F 21.2800 -25.5500
34 C8x C 30.2400 -25.6200
35 C8x C 30.2400 -27.0200
36 C8y C 31.4524 -27.7200
37 C8x C 32.6649 -27.0200
38 C8x C 32.6649 -25.6200
39 C8y C 31.4524 -24.9200
40 S4a S 31.4524 -23.5202
41 O1d O 32.8524 -23.5202
42 O1d O 30.0524 -23.5202
43 O1d O 31.4524 -22.1202
44 C1a C 31.4524 -29.1198
BOND 47
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 5 7 2
8 7 8 1
9 8 9 2
10 9 10 1
11 6 10 2
12 1 11 1
13 2 12 2
14 7 13 1
15 9 14 1
16 14 15 1
17 15 16 1
18 15 17 1
19 17 18 1
20 16 19 1
21 13 20 2
22 20 21 1
23 21 22 2
24 22 23 1
25 23 24 2
26 13 24 1
27 20 25 1
28 22 26 1
29 11 27 1
30 27 28 2
31 28 29 1
32 29 30 2
33 30 31 1
34 11 31 2
35 31 32 1
36 27 33 1
37 34 35 2
38 35 36 1
39 36 37 2
40 37 38 1
41 38 39 2
42 34 39 1
43 39 40 1
44 40 41 2
45 40 42 2
46 40 43 1
47 36 44 1
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