KEGG   DRUG: Taliglucerase alfaHelp
Entry
D09675                      Drug                                   

Name
Taliglucerase alfa (USAN/INN);
Alfataliglucerase;
Elelyso (TN);
Uplyso (TN)
Product
Formula
C2580H3918N680O727S17
Exact mass
56602.5769
Mol weight
56637.9397
Sequence
EFARPCIPKS FGYSSVVCVC NATYCDSFDP PTFPALGTFS RYESTRSGRR MELSMGPIQA
NHTGTGLLLT LQPEQKFQKV KGFGGAMTDA AALNILALSP PAQNLLLKSY FSEEGIGYNI
IRVPMASCDF SIRTYTYADT PDDFQLHNFS LPEEDTKLKI PLIHRALQLA QRPVSLLASP
WTSPTWLKTN GAVNGKGSLK GQPGDIYHQT WARYFVKFLD AYAEHKLQFW AVTAENEPSA
GLLSGYPFQC LGFTPEHQRD FIARDLGPTL ANSTHHNVRL LMLDDQRLLL PHWAKVVLTD
PEAAKYVHGI AVHWYLDFLA PAKATLGETH RLFPNTMLFA SEACVGSKFW EQSVRLGSWD
RGMQYSHSII TNLLYHVVGW TDWNLALNPE GGPNWVRNFV DSPIIVDITK DTFYKQPMFY
HLGHFSKFIP EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG
FLETISPGYS IHTYLWHRQD LLVDTM (Disulfide bridge: 6-18; 20-25)
  Type
Peptide
Remark
ATC code: A16AB11
Product: D09675<US>
Efficacy
Enzyme replenisher (glucosylceramidase)
  Disease
Type 1 Gaucher disease [DS:H00126]
Comment
plant-derived recombinant glucosylceramidase [KO:K01201] [EC:3.2.1.45]
Treatment of Gaucher disease type 1
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AB Enzymes
     A16AB11 Taliglucerase alfa
      D09675  Taliglucerase alfa (USAN/INN) <US>
USP drug classification [BR:br08302]
 Genetic or Enzyme Disorder: Replacement, Modifiers, Treatment
  Taliglucerase alfa
   D09675  Taliglucerase alfa (USAN/INN)
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D09675
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09675
BRITE hierarchy
Other DBs
CAS: 37228-64-1
PubChem: 124490415
LinkDB All DBs

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