KEGG   DRUG: Tecarfarin
Entry
D09676                      Drug                                   
Name
Tecarfarin (USAN/INN)
Formula
C21H14F6O5
Exact mass
460.0745
Mol weight
460.3233
Structure
Simcomp
Class
Blood modifier agent
 DG01950  Antithrombotic agent
  DG01708  Coumarin anticoagulant
   DG01760  Warfarin and analog
Remark
Chemical structure group: DG01390
Efficacy
Anticoagulant
Comment
coumarin derivative
Target
VKORC1 [HSA:79001] [KO:K05357]
  Pathway
hsa00130  Ubiquinone and other terpenoid-quinone biosynthesis
Interaction
Brite
Drug groups [BR:br08330]
 Blood modifier agent
  DG01950  Antithrombotic agent
   DG01708  Coumarin anticoagulant
    DG01760  Warfarin and analog
     DG01390  Tecarfarin
      D09676  Tecarfarin
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Vitamin-K-epoxide reductase
    VKORC1
     D09676  Tecarfarin (USAN/INN)
Drug groups [BR:br08330]
 Blood modifier agent
  DG01950  Antithrombotic agent
   DG01708  Coumarin anticoagulant
    DG01760  Warfarin and analog
     DG01390  Tecarfarin
Other DBs
CAS: 867257-26-9
PubChem: 124490416
LigandBox: D09676
LinkDB
KCF data

ATOM        32
            1   C8x C    13.6500  -23.1700
            2   C8x C    13.6500  -24.5700
            3   C8x C    14.8624  -25.2700
            4   C8y C    16.0749  -24.5700
            5   C8y C    16.0749  -23.1700
            6   C8x C    14.8624  -22.4700
            7   C8y C    17.2873  -25.2700
            8   C8y C    18.4997  -24.5700
            9   C8y C    18.4997  -23.1700
            10  O7x O    17.2873  -22.4700
            11  C1b C    19.6973  -25.2615
            12  C8y C    20.8856  -24.5755
            13  C8x C    22.0764  -25.2631
            14  C8x C    23.2889  -24.5633
            15  C8y C    23.2890  -23.1633
            16  C8x C    22.0982  -22.4756
            17  C8x C    20.8857  -23.1755
            18  C7a C    24.5142  -22.4559
            19  O7a O    25.7220  -23.1532
            20  C1d C    26.9032  -22.4713
            21  O6a O    24.5140  -21.0701
            22  C1d C    26.9032  -21.0713
            23  X   F    28.0987  -20.3809
            24  X   F    25.6729  -20.3609
            25  X   F    26.9032  -19.6713
            26  C1d C    28.3032  -22.4713
            27  C1a C    26.9032  -23.8713
            28  X   F    28.9966  -23.6727
            29  X   F    28.9978  -21.2680
            30  X   F    29.7032  -22.4713
            31  O6a O    19.6973  -22.4785
            32  O1a O    17.2873  -26.6700
BOND        34
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 1
            14   12  13 2
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   12  17 1
            20   15  18 1
            21   18  19 1
            22   19  20 1
            23   18  21 2
            24   20  22 1
            25   22  23 1
            26   22  24 1
            27   22  25 1
            28   20  26 1
            29   20  27 1
            30   26  28 1
            31   26  29 1
            32   26  30 1
            33    9  31 2
            34    7  32 1

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