| Entry |
|
|---|
| Name |
Tecarfarin (USAN/INN) |
|---|
| Formula |
C21H14F6O5
|
|---|
| Exact mass |
460.0745
|
|---|
| Mol weight |
460.32
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
|
|---|
| Remark |
|
|---|
| Efficacy |
Anticoagulant |
|---|
| Comment |
Coumarin derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
DG01390 Tecarfarin
D09676 Tecarfarin
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Vitamin-K-epoxide reductase
VKORC1
D09676 Tecarfarin (USAN/INN)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
DG01390 Tecarfarin
|
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| Other DBs |
|
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| LinkDB |
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| KCF data |
ATOM 32
1 C8x C 13.6500 -23.1700
2 C8x C 13.6500 -24.5700
3 C8x C 14.8624 -25.2700
4 C8y C 16.0749 -24.5700
5 C8y C 16.0749 -23.1700
6 C8x C 14.8624 -22.4700
7 C8y C 17.2873 -25.2700
8 C8y C 18.4997 -24.5700
9 C8y C 18.4997 -23.1700
10 O7x O 17.2873 -22.4700
11 C1b C 19.6973 -25.2615
12 C8y C 20.8856 -24.5755
13 C8x C 22.0764 -25.2631
14 C8x C 23.2889 -24.5633
15 C8y C 23.2890 -23.1633
16 C8x C 22.0982 -22.4756
17 C8x C 20.8857 -23.1755
18 C7a C 24.5142 -22.4559
19 O7a O 25.7220 -23.1532
20 C1d C 26.9032 -22.4713
21 O6a O 24.5140 -21.0701
22 C1d C 26.9032 -21.0713
23 X F 28.0987 -20.3809
24 X F 25.6729 -20.3609
25 X F 26.9032 -19.6713
26 C1d C 28.3032 -22.4713
27 C1a C 26.9032 -23.8713
28 X F 28.9966 -23.6727
29 X F 28.9978 -21.2680
30 X F 29.7032 -22.4713
31 O6a O 19.6973 -22.4785
32 O1a O 17.2873 -26.6700
BOND 34
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 1
13 11 12 1
14 12 13 2
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 12 17 1
20 15 18 1
21 18 19 1
22 19 20 1
23 18 21 2
24 20 22 1
25 22 23 1
26 22 24 1
27 22 25 1
28 20 26 1
29 20 27 1
30 26 28 1
31 26 29 1
32 26 30 1
33 9 31 2
34 7 32 1
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