| Entry |
|
|---|
| Name |
Tedizolid phosphate (JAN/USAN);
Torezolid phosphate;
Sivextro (TN) |
|---|
| Product |
|
|---|
| Formula |
C17H16FN6O6P
|
|---|
| Exact mass |
450.0853
|
|---|
| Mol weight |
450.3177
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01789 Oxazolidinone antibiotic
|
|---|
| Remark |
| Therapeutic category: | 6249 |
| Product (DG01442): | D09686<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Target |
50S ribosomal subunit |
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01X OTHER ANTIBACTERIALS
J01XX Other antibacterials
J01XX11 Tedizolid
D09686 Tedizolid phosphate (JAN/USAN) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Antibacterials, Other
Tedizolid
D09686 Tedizolid phosphate (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
624 Synthetic antibacterials
6249 Others
D09686 Tedizolid phosphate (JAN/USAN)
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Oxazolidinone
D09686 Tedizolid phosphate (JAN/USAN) <JP/US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D09686
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D09686
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D09686
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D09686
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Oxazolidinone
DG01442 Tedizolid
|
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| Other DBs |
|
|---|
| LinkDB |
|
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| KCF data |
ATOM 31
1 C8x C 17.2200 -15.8200
2 C8y C 17.2200 -17.2200
3 C8x C 18.4100 -17.9200
4 C8x C 19.6700 -17.2200
5 C8y C 19.6700 -15.8200
6 C8y C 18.4100 -15.1200
7 C8y C 20.8600 -15.0500
8 C8x C 22.1200 -15.7500
9 N5x N 23.3100 -15.0500
10 C8y C 23.3100 -13.6500
11 C8x C 22.1200 -12.9500
12 C8x C 20.8600 -13.6500
13 C8y C 24.5700 -12.9500
14 X F 18.4100 -13.7200
15 N1y N 16.0300 -17.9200
16 C1x C 14.7000 -17.5000
17 C1y C 13.9300 -18.6200
18 O7x O 14.7700 -19.7400
19 C7x C 16.0300 -19.3200
20 O6a O 17.2200 -20.0900
21 C1b C 12.5300 -18.6900
22 N5x N 25.9000 -13.3700
23 N4y N 26.7400 -12.1800
24 N5x N 25.9000 -11.0600
25 N5x N 24.5700 -11.5500
26 C1a C 28.1400 -12.1800
27 O2b O 11.7600 -17.5000
28 P1b P 10.3600 -17.5000
29 O1c O 10.3600 -16.1000
30 O1c O 10.3600 -18.9000
31 O1c O 8.9600 -17.5000
BOND 34
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 7 12 1
14 10 13 1
15 6 14 1
16 2 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 15 19 1
22 19 20 2
23 17 21 1 #Up
24 13 22 2
25 22 23 1
26 23 24 1
27 24 25 2
28 13 25 1
29 23 26 1
30 21 27 1
31 27 28 1
32 28 29 1
33 28 30 2
34 28 31 1
|
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