| Entry |
|
|---|
| Name |
Gantenerumab (USAN/INN);
Gantenerumab (genetical recombination) (JAN) |
|---|
| Formula |
C6496H10072N1740O2024S42
|
|---|
| Exact mass |
146184.6967
|
|---|
| Mol weight |
146274.73
|
|---|
| Sequence |
(gamma1-heavy chain) QVELVESGGG LVQPGGSLRL SCAASGFTFS SYAMSWVRQA
PGKGLEWVSA INASGTRTYY ADSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCARGK
GNTHKPYGYV RYFDVWGQGT LVTVSSASTK GPSVFPLAPS SKSTSGGTAA LGCLVKDYFP
EPVTVSWNSG ALTSGVHTFP AVLQSSGLYS LSSVVTVPSS SLGTQTYICN VNHKPSNTKV
DKKVEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP
EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP
IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY
KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGK
(kappa-light chain) DIVLTQSPAT LSLSPGERAT LSCRASQSVS SSYLAWYQQK
PGQAPRLLIY GASSRATGVP ARFSGSGSGT DFTLTISSLE PEDFATYYCL QIYNMPITFG
QGTKVEIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS
QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC |
|---|
| Type |
Peptide |
|---|
| Efficacy |
Dementia therapeutic agent |
|---|
| Type |
Monoclonal antibody |
|---|
| Comment |
Treatment of Alzheimer's disease
|
|---|
| Target |
|
|---|
| Structure map |
| map07056 | Agents for Alzheimer-type dementia |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
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|---|
