KEGG   DRUG: LixisenatideHelp
Entry
D09729                      Drug                                   

Name
Lixisenatide (JAN/INN);
Adlyxin (TN);
Lyxumia (TN)
Product
Formula
C215H347N61O65S
Exact mass
4855.5443
Mol weight
4858.4904
Sequence
His Gly Glu Gly Thr Phe Thr Ser Asp Leu Ser Lys Gln Met Glu Glu
Glu Ala Val Arg Leu Phe Ile Glu Trp Leu Lys Asn Gly Gly Pro Ser
Ser Gly Ala Pro Pro Ser Lys Lys Lys Lys Lys Lys
  Type
Peptide
Class
Antidiabetic agent
 DG01493  GLP-1 receptor agonist
 DG02044  Hypoglycemics
  DG01493  GLP-1 receptor agonist
Remark
Therapeutic category: 2499
ATC code: A10BJ03
Product: D09729<JP/US>
Product (mixture): D11034<US>
Efficacy
Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist
  Disease
Type 2 diabetes mellitus [DS:H00409]
Target
GLP1R [HSA:2740] [KO:K04581]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
Interaction
Drug interaction
Structure map
map07051  Antidiabetics
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BJ Glucagon-like peptide-1 receptor (GLP-1) analogues
     A10BJ03 Lixisenatide
      D09729  Lixisenatide (JAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Antidiabetic Agents
   Lixisenatide
    D09729  Lixisenatide (JAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D09729  Lixisenatide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D09729  Lixisenatide (JAN/INN) <JP/US>
Drug classes of therapeutic agents [br08360.html]
 Antidiabetic agents
  D09729
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D09729
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09729
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09729
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09729
BRITE hierarchy
Other DBs
CAS: 320367-13-3
PubChem: 124490469
ChEBI: 85662
LinkDB All DBs

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