KEGG   DRUG: Darexaban maleate
Entry
D09817                      Drug                                   
Name
Darexaban maleate (JAN);
YM150
Formula
C27H30N4O4. C4H4O4
Exact mass
590.2377
Mol weight
590.6237
Structure
Class
Blood modifier agent
 DG01950  Antithrombotic agent
  DG01662  Factor Xa inhibitor
Efficacy
Anticoagulant, Antithrombotic, Factor Xa inhibitor
Target
F10 [HSA:2159] [KO:K01314]
  Pathway
hsa04610  Complement and coagulation cascades
Interaction
Structure map
map07049  Antithrombosis agents
Brite
Drug groups [BR:br08330]
 Blood modifier agent
  DG01950  Antithrombotic agent
   DG01662  Factor Xa inhibitor
    D09817  Darexaban maleate
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Serine peptidases
    F10
     D09817  Darexaban maleate (JAN)
Other DBs
PubChem: 124490557
LigandBox: D09817
LinkDB
KCF data

ATOM        43
            1   C1x C    16.8700  -26.6700
            2   C1x C    17.9900  -25.7600
            3   N1y N    19.3200  -26.1100
            4   C1x C    19.9500  -27.3700
            5   C1x C    16.8700  -28.0700
            6   C1x C    19.3200  -28.6300
            7   N1y N    17.9900  -28.9100
            8   C8x C    20.5100  -24.0100
            9   C8y C    20.5100  -25.4100
            10  C8x C    21.7000  -26.1100
            11  C8x C    22.9600  -25.4100
            12  C8y C    22.9600  -24.0100
            13  C8x C    21.7000  -23.3100
            14  C5a C    24.1500  -23.3100
            15  N1b N    25.3400  -24.0100
            16  C8y C    26.5300  -23.3100
            17  O5a O    24.1500  -22.0500
            18  C8y C    27.7200  -24.0100
            19  C8x C    28.9800  -23.3100
            20  C8x C    28.9800  -21.9100
            21  C8x C    27.7900  -21.2100
            22  C8y C    26.5300  -21.9100
            23  N1b N    27.7200  -25.4100
            24  C5a C    28.9100  -26.1100
            25  C8y C    30.1000  -25.4100
            26  O5a O    28.9100  -27.5100
            27  C8x C    31.2900  -26.1100
            28  C8x C    32.5500  -25.4100
            29  C8y C    32.5500  -24.0100
            30  C8x C    31.3600  -23.3100
            31  C8x C    30.1000  -24.0100
            32  O2a O    33.7400  -23.3100
            33  C1a C    34.9300  -24.0100
            34  C1a C    17.6872  -30.2769
            35  O1a O    25.3234  -21.2000
            36  C2b C    24.1500  -28.5600
            37  C2b C    25.9000  -28.5600
            38  C6a C    26.6000  -29.7724
            39  C6a C    23.4500  -29.7724
            40  O6a O    22.0502  -29.7724
            41  O6a O    24.1404  -30.9679
            42  O6a O    27.9998  -29.7724
            43  O6a O    25.9096  -30.9679
BOND        45
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     8   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13    8  13 1
            14    9   3 1
            15   12  14 1
            16   14  15 1
            17   15  16 1
            18   14  17 2
            19   16  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   16  22 2
            25   18  23 1
            26   23  24 1
            27   24  25 1
            28   24  26 2
            29   25  27 1
            30   27  28 2
            31   28  29 1
            32   29  30 2
            33   30  31 1
            34   25  31 2
            35   29  32 1
            36   32  33 1
            37    7  34 1
            38   22  35 1
            39   36  37 2
            40   37  38 1
            41   36  39 1
            42   39  40 1
            43   39  41 2
            44   38  42 2
            45   38  43 1

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