KEGG   DRUG: Darexaban maleate
Entry
D09817                      Drug                                   

Name
Darexaban maleate (JAN);
YM150
Formula
C27H30N4O4. C4H4O4
Exact mass
590.2377
Mol weight
590.6237
Structure
Class
Cardiovascular agent
 DG01662  Factor Xa inhibitor
 DG01950  Antithrombotic agent
  DG01662  Factor Xa inhibitor
Efficacy
Anticoagulant, Antithrombotic, Factor Xa inhibitor
Target
F10 [HSA:2159] [KO:K01314]
  Pathway
hsa04610  Complement and coagulation cascades
Interaction
Structure map
map07049  Antithrombosis agents
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Serine peptidases
    F10
     D09817  Darexaban maleate (JAN)
Other DBs
PubChem: 124490557
ChEMBL: CHEMBL1922345
LigandBox: D09817
LinkDB
KCF data

ATOM        43
            1   C1x C    16.8700  -26.6700
            2   C1x C    17.9900  -25.7600
            3   N1y N    19.3200  -26.1100
            4   C1x C    19.9500  -27.3700
            5   C1x C    16.8700  -28.0700
            6   C1x C    19.3200  -28.6300
            7   N1y N    17.9900  -28.9100
            8   C8x C    20.5100  -24.0100
            9   C8y C    20.5100  -25.4100
            10  C8x C    21.7000  -26.1100
            11  C8x C    22.9600  -25.4100
            12  C8y C    22.9600  -24.0100
            13  C8x C    21.7000  -23.3100
            14  C5a C    24.1500  -23.3100
            15  N1b N    25.3400  -24.0100
            16  C8y C    26.5300  -23.3100
            17  O5a O    24.1500  -22.0500
            18  C8y C    27.7200  -24.0100
            19  C8x C    28.9800  -23.3100
            20  C8x C    28.9800  -21.9100
            21  C8x C    27.7900  -21.2100
            22  C8y C    26.5300  -21.9100
            23  N1b N    27.7200  -25.4100
            24  C5a C    28.9100  -26.1100
            25  C8y C    30.1000  -25.4100
            26  O5a O    28.9100  -27.5100
            27  C8x C    31.2900  -26.1100
            28  C8x C    32.5500  -25.4100
            29  C8y C    32.5500  -24.0100
            30  C8x C    31.3600  -23.3100
            31  C8x C    30.1000  -24.0100
            32  O2a O    33.7400  -23.3100
            33  C1a C    34.9300  -24.0100
            34  C1a C    17.6872  -30.2769
            35  O1a O    25.3234  -21.2000
            36  C2b C    24.1500  -28.5600
            37  C2b C    25.9000  -28.5600
            38  C6a C    26.6000  -29.7724
            39  C6a C    23.4500  -29.7724
            40  O6a O    22.0502  -29.7724
            41  O6a O    24.1404  -30.9679
            42  O6a O    27.9998  -29.7724
            43  O6a O    25.9096  -30.9679
BOND        45
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     8   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13    8  13 1
            14    9   3 1
            15   12  14 1
            16   14  15 1
            17   15  16 1
            18   14  17 2
            19   16  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   16  22 2
            25   18  23 1
            26   23  24 1
            27   24  25 1
            28   24  26 2
            29   25  27 1
            30   27  28 2
            31   28  29 1
            32   29  30 2
            33   30  31 1
            34   25  31 2
            35   29  32 1
            36   32  33 1
            37    7  34 1
            38   22  35 1
            39   36  37 2
            40   37  38 1
            41   36  39 1
            42   39  40 1
            43   39  41 2
            44   38  42 2
            45   38  43 1

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