| Entry |
|
|---|
| Name |
Levormeloxifene fumarate (JAN) |
|---|
| Formula |
C30H35NO3. C4H4O4
|
|---|
| Exact mass |
573.2727
|
|---|
| Mol weight |
573.67
|
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| Structure |
|
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| Simcomp |
|
|---|
| Class |
Hormonal agent
DG01619 Estrogen receptor antagonist/modulator
DG01621 Selective estrogen receptor modulator
|
|---|
| Efficacy |
Osteoporosis agent, Selective estrogen receptor modulator (SERM) |
|---|
| Comment |
Clomifene, tamoxifen derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04961 | Endocrine and other factor-regulated calcium reabsorption |
|
|---|
| Brite |
Drug groups [BR:br08330]
Hormonal agent
DG01619 Estrogen receptor antagonist/modulator
DG01621 Selective estrogen receptor modulator
D09834 Levormeloxifene fumarate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
Estrogen receptor
NR3A (ESR)
D09834 Levormeloxifene fumarate (JAN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 42
1 C6a C 29.3710 -22.5666
2 C2b C 30.5816 -23.2656
3 O6a O 28.1605 -23.2656
4 C2b C 31.7752 -22.5762
5 C6a C 32.9607 -23.2607
6 O6a O 34.1501 -22.5737
7 O6a O 29.3710 -21.1688
8 O6a O 32.9609 -24.6632
9 C8y C 16.8700 -22.5400
10 C8x C 16.8700 -23.9400
11 C8x C 18.0600 -24.6400
12 C8y C 19.3200 -23.9400
13 C8x C 19.3200 -22.5400
14 C8x C 18.0600 -21.8400
15 O2a O 20.5100 -24.7100
16 C1b C 21.7700 -24.0100
17 C1b C 22.9600 -24.6400
18 N1y N 24.1500 -23.9400
19 C1x C 25.4644 -24.4065
20 C1x C 26.2758 -23.2443
21 C1x C 25.4032 -22.1630
22 C1x C 24.1268 -22.6084
23 C1y C 15.6800 -21.8400
24 C1y C 15.6800 -20.4400
25 C1z C 14.4200 -19.7400
26 O2x O 13.2300 -20.4400
27 C8y C 13.2300 -21.8400
28 C8y C 14.4200 -22.5400
29 C8x C 11.9700 -22.5400
30 C8y C 11.9700 -23.9400
31 C8x C 13.2300 -24.6400
32 C8x C 14.4200 -23.9400
33 O2a O 10.7800 -24.6400
34 C1a C 9.5900 -23.9400
35 C8y C 16.8700 -19.7400
36 C8x C 18.0600 -20.4400
37 C8x C 19.3200 -19.7400
38 C8x C 19.3200 -18.3400
39 C8x C 18.1300 -17.6400
40 C8x C 16.8700 -18.3400
41 C1a C 13.4400 -18.7600
42 C1a C 15.4000 -18.7600
BOND 45
1 1 2 1
2 1 3 1
3 2 4 2
4 4 5 1
5 5 6 1
6 1 7 2
7 5 8 2
8 9 10 2
9 10 11 1
10 11 12 2
11 12 13 1
12 13 14 2
13 9 14 1
14 12 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 21 22 1
22 18 22 1
23 23 9 1 #Down
24 23 24 1
25 24 25 1
26 25 26 1
27 26 27 1
28 27 28 1
29 23 28 1
30 27 29 2
31 29 30 1
32 30 31 2
33 31 32 1
34 28 32 2
35 30 33 1
36 33 34 1
37 24 35 1 #Up
38 35 36 2
39 36 37 1
40 37 38 2
41 38 39 1
42 39 40 2
43 35 40 1
44 25 41 1
45 25 42 1
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