KEGG   DRUG: EnsituximabHelp
Entry
D09898                      Drug                                   

Name
Ensituximab (USAN/INN)
Formula
C6342H9800N1678O1985S46
Exact mass
142698.4643
Mol weight
142786.713
Sequence
(Heavy chain) QVQLKESGPD LVAPSQSLSI TCTVSGFSLS KFGVNWVRQP
PGKGLEWLGV IWGDGSTSYN SGLISRLSIS KENSKSQVFL KLNSLQADDT ATYYCVKPGG
DYWGHGTSVT VSSASTKGPS VFPLAPSSKS TSGGTAALGC LVKDYFPEPV TVSWNSGALT
SGVHTFPAVL QSSGPYSLSS VVTVPSSSLG TQTYICNVNH KPSNTKVDKK VEPKSCDKTH
TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV
HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR
EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTM PPVLDSDGSF
FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK
(Disulfide bridge: 22-95; 140-196; 257-317; 363-421, Dimer: 222; 225)
(Light chain) QVVLTQSPVI MSASPGEKVT MTCSASSSIS YMYWYQQKPG
TSPKRWIYDT SKLASGVPAR FSGSGSGTSY SLTISNMEAG DAATYYCHQR DSYPWTFGGG
TNLEIKRTVA APSVFIFPPS DEQLKSGTAS VVCLLNNFYP REAKVQWKVD NALQSGNSQE
SVTEQDSKDS TYSLSSTLTL SKADYEKHKV YACEVTHQGL SSPVTKSFNR GEC
(Disulfide bridge: 23-87; 133-193; H216-L213, Dimer)
  Type
Peptide
Efficacy
Antineoplastic
Comment
Monoclonal antibody
Other DBs
CAS: 1092658-06-4
PubChem: 124490611
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