KEGG   DRUG: SamalizumabHelp
Entry
D09961                      Drug                                   

Name
Samalizumab (USAN/INN)
Formula
C6542H10086N1702O2102S46
Exact mass
147594.181
Mol weight
147685.2144
Sequence
(Heavy chain) QVQLQQSGSE LKKPGASVKI SCKASGYSFT DYIILWVRQN
PGKGLEWIGH IDPYYGSSNY NLKFKGRVTI TADQSTTTAY MELSSLRSED TAVYYCGRSK
RDYFDYWGQG TTLTVSSAST KGPSVFPLAP CSRSTSESTA ALGCLVKDYF PEPVTVSWNS
GALTSGVHTF PAVLQSSGLY SLSSVVTVPS SNFGTQTYTC NVDHKPSNTK VDKTVERKCC
VECPPCPAPP VAGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSQEDPEVQ FNWYVDGVEV
HNAKTKPREE QFNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKGLPSSIEK TISKAKGQPR
EPQVYTLPPS QEEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF
FLYSRLTVDK SRWQEGNVFS CSVMHEALHN HYTQKSLSLS LG
(Disulfide bridge: 22-96; 144-200; 257-317; 363-421, Dimer: 219; 220; 223; 226)
(Light chain) DIQMTQSPSS LSASIGDRVT ITCKASQDIN SYLSWFQQKP
GKAPKLLIYR ANRLVDGVPS RFSGSGSGTD YTLTISSLQP EDFAVYYCLQ YDEFPYTFGG
GTKLEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ
ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(Disulfide bridge: 23-88; 134-194; H131-L214, Dimer)
  Type
Peptide
Efficacy
Antineoplastic, Anti-CD200 antibody
Comment
Monoclonal antibody
Target
CD200 [HSA:4345] [KO:K06556]
Brite
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   CD molecules
    CD200
     D09961  Samalizumab (USAN/INN)
BRITE hierarchy
Other DBs
PubChem: 124490632
LinkDB All DBs

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