KEGG   DRUG: SolithromycinHelp
Entry
D09965                      Drug                                   

Name
Solithromycin (JAN/USAN)
Formula
C43H65FN6O10
Exact mass
844.4746
Mol weight
845.0088
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
ATC code: J01FA16
Efficacy
Antibiotic, Protein biosynthesis inhibitor
Target
50S ribosomal subunit
  Pathway
ko03010  Ribosome
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FA Macrolides
     J01FA16 Solithromycin
      D09965  Solithromycin (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 760981-83-7
PubChem: 135626688
LigandBox: D09965
LinkDB All DBs
KCF data Show

ATOM        60
            1   C1y C    23.9364  -17.0659
            2   C5x C    22.7549  -17.7609
            3   C1y C    23.9364  -15.6760
            4   C1z C    22.7549  -19.0813
            5   C1z C    22.7549  -15.0505
            6   C7x C    21.5736  -19.7763
            7   C1x C    22.7549  -13.6606
            8   O7x O    20.3922  -19.0813
            9   C1y C    21.5736  -13.0351
            10  C1y C    20.3922  -17.7609
            11  C5x C    20.3922  -13.6606
            12  C1y C    20.3922  -15.0505
            13  O5x O    21.5736  -17.0659
            14  O6a O    21.5736  -21.0967
            15  C1z C    19.2107  -17.0659
            16  C1y C    19.2107  -15.6760
            17  C1a C    18.8632  -18.3168
            18  C1a C    19.2107  -14.3555
            19  O5x O    19.2107  -12.9656
            20  C1a C    21.5736  -11.6452
            21  O2a O    23.3804  -13.5216
            22  C1a C    24.2144  -14.4250
            23  O2a O    25.6043  -15.5370
            24  C1y C    26.9942  -16.0930
            25  C1y C    28.2452  -15.3980
            26  O2x O    27.0637  -17.4134
            27  C1y C    29.4266  -16.0930
            28  O1a O    28.3147  -14.0776
            29  C1y C    28.2452  -18.1778
            30  C1x C    29.4266  -17.4829
            31  N1c N    30.6080  -15.4675
            32  C1a C    28.2452  -19.4983
            33  C1a C    31.7895  -16.0930
            34  C1a C    30.6080  -14.0776
            35  C1a C    25.1178  -17.7609
            36  C1b C    19.4192  -18.6643
            37  C1a C    19.4192  -19.9848
            38  C1a C    23.3804  -12.2012
            39  N1y N    17.3343  -15.2590
            40  C7x C    16.5004  -16.3709
            41  O7x O    17.3343  -17.4829
            42  O6a O    15.1104  -16.3709
            43  C1b C    17.3343  -13.8691
            44  C1b C    16.1529  -13.1741
            45  C1b C    14.9714  -13.8691
            46  C1b C    13.7900  -13.1741
            47  N4y N    12.6086  -13.8691
            48  C8x C    11.4877  -13.0471
            49  C8y C    10.3597  -13.8590
            50  N5x N    10.7833  -15.1829
            51  N5x N    12.1732  -15.1891
            52  C8y C     9.0652  -13.4321
            53  C8x C     9.0684  -12.0622
            54  C8x C     7.8643  -11.3679
            55  C8x C     6.6611  -12.0636
            56  C8y C     6.6619  -13.4341
            57  C8x C     7.8659  -14.1284
            58  N1a N     5.4283  -14.1473
            59  C1a C    22.7549  -20.4712
            60  X   F    24.1449  -19.0813
BOND        64
            1    11  19 2
            2     4   6 1
            3     9  20 1 #Down
            4     5   7 1
            5     5  21 1 #Up
            6     6   8 1
            7     5  22 1 #Down
            8     7   9 1
            9     8  10 1
            10    9  11 1
            11   10  15 1
            12   11  12 1
            13   12  16 1
            14    2  13 2
            15    6  14 2
            16   24  23 1 #Up
            17   24  25 1
            18   24  26 1
            19   25  27 1
            20   25  28 1 #Down
            21   26  29 1
            22   27  30 1
            23   27  31 1 #Up
            24   29  32 1 #Up
            25   31  33 1
            26   31  34 1
            27   29  30 1
            28    3  23 1 #Down
            29    1  35 1 #Up
            30    1   2 1
            31   15  16 1
            32    1   3 1
            33   15  17 1 #Down
            34   10  36 1 #Up
            35    2   4 1
            36   36  37 1
            37   12  18 1 #Up
            38    3   5 1
            39   21  38 1
            40   16  39 1 #Down
            41   39  40 1
            42   40  41 1
            43   15  41 1
            44   40  42 2
            45   39  43 1
            46   44  43 1
            47   44  45 1
            48   45  46 1
            49   46  47 1
            50   47  48 1
            51   48  49 2
            52   49  50 1
            53   50  51 2
            54   47  51 1
            55   49  52 1
            56   52  53 2
            57   53  54 1
            58   54  55 2
            59   55  56 1
            60   56  57 2
            61   52  57 1
            62   56  58 1
            63    4  59 1 #Down
            64    4  60 1 #Up

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