KEGG   DRUG: Epoetin beta pegol
Entry
D09998                      Drug                                   
Name
Epoetin beta pegol (genetical recombination) (JAN);
Methoxy polyethylene glycol - epoetin beta;
Mircera (TN)
Product
MIRCERA (Vifor (International))
Formula
C809H1301N229O240S5
Exact mass
18224.5242
Mol weight
18235.71
Sequence
APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA
VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS
PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGD
(Disulfide bridge: 7-161, 29-33)
  Type
Peptide
Remark
Therapeutic category: 3999
ATC code: B03XA03
Product: D09998<JP/US>
Efficacy
Anti-anemic, Erythropoietin receptor agonist
  Disease
Anemia due to chronic kidney disease [DS:H01642]
Comment
See erythropoietin [CPD:C18200] [hsa:2056] [KO:K05437]
Continuous erythropoietin receptor activator
Target
EPOR [HSA:2057] [KO:K05079]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B03 ANTIANEMIC PREPARATIONS
   B03X OTHER ANTIANEMIC PREPARATIONS
    B03XA Other antianemic preparations
     B03XA03 Methoxy polyethylene glycol-epoetin beta
      D09998  Epoetin beta pegol (genetical recombination) (JAN) <JP/US>
USP drug classification [BR:br08302]
 Blood Products and Modifiers
  Erythropoiesis Promoters
   Erythropoiesis-Stimulating Agents
    Methoxy Polyethylene Glycol-Epoetin Beta
     D09998  Epoetin beta pegol (genetical recombination) (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D09998  Epoetin beta pegol (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    EPOR
     D09998  Epoetin beta pegol (genetical recombination) (JAN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D09998
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09998
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09998
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09998
Other DBs
CAS: 677324-53-7
PubChem: 135626719
LinkDB

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