| Entry |
|
|---|
| Name |
Ioflupane I 123 (USAN);
Datscan (TN) |
|---|
| Product |
|
|---|
| Formula |
C18H23FINO2
|
|---|
| Exact mass |
427.0769
|
|---|
| Mol weight |
431.2836
|
|---|
| Structure |
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|---|
| Simcomp |
|
|---|
| Remark |
| Therapeutic category: | 4300 |
|
|---|
| Efficacy |
Diagnostic (SPECT imaging) |
|---|
| Comment |
Diagnosis of Parkinson's disease (visualization for dopamine transporters: SLC6A3 (DAT1) [HSA: 6531] [KO: K05036])
|
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| Target |
|
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
V VARIOUS
V09 DIAGNOSTIC RADIOPHARMACEUTICALS
V09A CENTRAL NERVOUS SYSTEM
V09AB Iodine (123I) compounds
V09AB03 Iodine ioflupane (123I)
D10014 Ioflupane I 123 (USAN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
43 Radioactive drugs
430 Radioactive drugs
4300 Radioactive drugs
D10014 Ioflupane I 123 (USAN)
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A3 (DAT1)
D10014 Ioflupane I 123 (USAN) <JP/US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D10014
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D10014
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D10014
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D10014
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 23
1 C1x C 20.4400 -20.9300
2 C1x C 20.7900 -19.7400
3 C1y C 21.6300 -20.6500
4 C1y C 21.9800 -19.4600
5 N1y N 20.7200 -18.1300
6 C1x C 23.5200 -20.6500
7 C1y C 23.2400 -19.4600
8 C1y C 24.5700 -21.2100
9 C8y C 25.6200 -22.0500
10 C8x C 26.3200 -23.3100
11 C8x C 27.7200 -23.3100
12 C8y C 28.4200 -22.0500
13 C8x C 27.7200 -20.8600
14 C8x C 26.3200 -20.8600
15 X I 30.2400 -22.0500
16 C7a C 23.8700 -18.2000
17 O7a O 25.2700 -18.2000
18 O6a O 23.1000 -17.0100
19 C1a C 25.9700 -17.0100
20 C1b C 19.5300 -17.4300
21 C1b C 18.3400 -18.1300
22 C1b C 17.1500 -17.4300
23 X F 15.9600 -18.1300
BOND 25
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 3 6 1
6 4 7 1
7 6 8 1
8 8 9 1 #Up
9 4 5 1
10 7 8 1
11 9 10 2
12 10 11 1
13 11 12 2
14 12 13 1
15 13 14 2
16 9 14 1
17 12 15 1
18 7 16 1 #Up
19 16 17 1
20 16 18 2
21 17 19 1
22 20 5 1
23 20 21 1
24 21 22 1
25 22 23 1
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