KEGG   DRUG: SemaglutideHelp
Entry
D10025                      Drug                                   

Name
Semaglutide (USAN/INN);
Semaglutide (genetical recombination) (JAN);
Ozempic (TN)
Product
Formula
C187H291N45O59
Exact mass
4111.1154
Mol weight
4113.5775
Sequence
HXEGTFTSDV SSYLEGQAAK EFIAWLVRGR G
  Type
Peptide
Class
Antidiabetic agent
 DG01493  GLP-1 receptor agonist
 DG02044  Hypoglycemics
  DG01493  GLP-1 receptor agonist
Remark
Therapeutic category: 2499
ATC code: A10BJ06
Product: D10025<JP/US>
Efficacy
Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist
  Disease
Type 2 diabetes mellitus [DS:H00409]
Target
GLP1R [HSA:2740] [KO:K04581]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BJ Glucagon-like peptide-1 receptor (GLP-1) analogues
     A10BJ06 Semaglutide
      D10025  Semaglutide (USAN/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D10025  Semaglutide (USAN/INN); Semaglutide (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D10025  Semaglutide (USAN/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D10025
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10025
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D10025
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10025
BRITE hierarchy
Other DBs
CAS: 910463-68-2
PubChem: 172232422
LinkDB All DBs

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