KEGG   DRUG: Cenderitide
Entry
D10063                      Drug                                   
Name
Cenderitide (USAN)
Formula
C158H263N49O50S3
Exact mass
3742.8706
Mol weight
3745.28
Structure
Sequence
GLSKGCFGLK LDRIGSMSGL GCPSLRDPRP NAPSTSA
(dislfide brige: 6-22)
  Type
Peptide
Efficacy
Antihypertensive, Diuretic, Atrial natriuretic peptide receptor agonist
  Type
Modified peptide
Comment
designer natriuretic peptide
Treatment of acute, decompensated heart failure
Target
NPR1 [HSA:4881] [KO:K12323]
  Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04270  Vascular smooth muscle contraction
Brite
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Serine/threonine kinases
   Other
    NPR1
     D10063  Cenderitide (USAN)
Other DBs
PubChem: 135626783
LinkDB

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