| Entry |
|
|---|
| Name |
Dexmecamylamine (USAN) |
|---|
| Formula |
C11H21N
|
|---|
| Exact mass |
167.1674
|
|---|
| Mol weight |
167.29
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant, Nicotinic acetylcholine receptor alpha4/beta2 antagonist |
|---|
| Comment |
Treatment of major depressive disorder
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRNA4/CHRNB2
D10111 Dexmecamylamine (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 12
1 C1z C 25.1047 -20.7675
2 C1y C 23.9160 -20.0683
3 C1z C 25.1047 -22.1660
4 C1x C 23.4265 -21.3968
5 C1x C 22.6574 -20.7675
6 C1y C 23.9160 -22.7953
7 C1x C 22.6574 -22.1660
8 C1a C 26.2934 -20.0683
9 C1a C 26.2934 -22.8652
10 C1a C 25.1047 -23.5645
11 N1b N 25.1047 -19.3690
12 C1a C 26.2934 -18.6698
BOND 13
1 1 2 1
2 1 3 1
3 2 4 1
4 2 5 1 #Up
5 3 6 1
6 5 7 1
7 6 4 1
8 6 7 1 #Up
9 1 8 1 #Up
10 3 9 1
11 3 10 1
12 1 11 1 #Down
13 11 12 1
|
|---|
