| Entry |
|
|---|
| Name |
Dexmecamylamine hydrochloride (USAN) |
|---|
| Formula |
C11H21N. HCl
|
|---|
| Exact mass |
203.1441
|
|---|
| Mol weight |
203.75
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant, Nicotinic acetylcholine receptor alpha4/beta2 antagonist |
|---|
| Comment |
Treatment of major depressive disorder
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRNA4/CHRNB2
D10112 Dexmecamylamine hydrochloride (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 13
1 C1z C 25.1300 -20.5100
2 C1y C 23.9400 -19.8100
3 C1z C 25.1300 -21.9100
4 C1x C 23.4500 -21.1400
5 C1x C 22.6800 -20.5100
6 C1y C 23.9400 -22.5400
7 C1x C 22.6800 -21.9100
8 C1a C 26.3200 -19.8100
9 C1a C 26.3200 -22.6100
10 C1a C 25.1300 -23.3100
11 N1b N 25.1300 -19.1100
12 C1a C 26.3200 -18.4100
13 X Cl 29.6800 -21.5600
BOND 13
1 1 2 1
2 1 3 1
3 2 4 1
4 2 5 1 #Up
5 3 6 1
6 5 7 1
7 6 4 1
8 6 7 1 #Up
9 1 8 1 #Up
10 3 9 1
11 3 10 1
12 1 11 1 #Down
13 11 12 1
|
|---|
